Yadav Rajni, Balasundaram Partheeban, Mridha Asit R, Iyer Venkateswaran K, Mathur Sandeep R
Address: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Cytojournal. 2016 Jan 28;13:2. doi: 10.4103/1742-6413.173588. eCollection 2016.
Lymphoma of the female genital tract is a rare condition. Involvement of the ovary by non- Hodgkin lymphoma (NHL) is usually secondary to systemic disease and primary ovarian lymphomas are unusual. In most cases, the diagnosis is not suspected initially and is confirmed only after detailed histopathological evaluation. We describe two cases of primary ovarian NHL which were diagnosed on fine needle aspiration cytology (FNAC). One of the patients was a 40 years old female who presented with abdominal distension and lump. She was found to have bilateral adnexal masses on ultrasound and computed tomography (CT) scan. A USG guided fine needle aspiration of the ovarian masses was performed, following which a diagnosis of primary ovarian diffuse large B-cell lymphoma was established. The second patient was a 14 years old female who presented with pelvic lump, which was lobulated and mildly enhancing on contrast enhanced CT. A diagnosis of high grade NHL of ovaries was made on cytology. Subsequently, the lymphoma was characterized as Burkitt's on histopathological examination. Both the patients were started on R-CHOP chemotherapy regimen. FNAC serves as an extremely useful minimally invasive procedure for the diagnosis of ovarian lymphomas and early institution of appropriate chemotherapeutic regimens.
女性生殖道淋巴瘤是一种罕见疾病。非霍奇金淋巴瘤（NHL）累及卵巢通常继发于全身性疾病，原发性卵巢淋巴瘤并不常见。在大多数情况下，最初并不会怀疑有该诊断，只有在详细的组织病理学评估后才能确诊。我们描述了两例经细针穿刺细胞学检查（FNAC）确诊的原发性卵巢NHL病例。其中一名患者是40岁女性，表现为腹胀和肿块。超声和计算机断层扫描（CT）检查发现她双侧附件有肿块。在超声引导下对卵巢肿块进行了细针穿刺，随后确诊为原发性卵巢弥漫性大B细胞淋巴瘤。第二名患者是14岁女性，表现为盆腔肿块，该肿块呈分叶状，在增强CT上有轻度强化表现。细胞学检查诊断为卵巢高级别NHL。随后，经组织病理学检查该淋巴瘤被确定为伯基特淋巴瘤。两名患者均开始接受R-CHOP化疗方案治疗。细针穿刺细胞学检查是诊断卵巢淋巴瘤以及早期制定合适化疗方案的一种极其有用且微创的方法。
