金耳内酯类似物的合成及细胞毒性
Synthesis and cytotoxicity of aurilide analogs.
作者信息
Suenaga Kiyotake, Kajiwara Shuri, Kuribayashi Satomi, Handa Tomohisa, Kigoshi Hideo
机构信息
Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku, Yokohama 223-8522, Japan.
出版信息
Bioorg Med Chem Lett. 2008 Jul 15;18(14):3902-5. doi: 10.1016/j.bmcl.2008.06.035. Epub 2008 Jun 14.
PMID:18583129
Abstract
The artificial analogs of aurilide (1), a potent cytotoxic cyclodepsipeptide of marine origin, were synthesized, and the structure-activity relationships were investigated.
摘要
合成了海洋来源的强效细胞毒性环缩肽奥瑞利德（1）的人工类似物，并研究了其构效关系。
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