Lee Woong Chul, Yang Hyeon Woong, Lee Yun Jung, Jung Sung Hee, Choi Gi Young, Go Hoon, Kim Anna, Cha Sang Woo
Division of Gastroenterology, Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea.
J Korean Med Sci. 2008 Jun;23(3):540-3. doi: 10.3346/jkms.2008.23.3.540.
Brunner's gland hyperplasia is a benign tumor of the duodenum and it is rarely associated with clinical symptoms. We report on a 64-yr-old man with Brunner's gland hyperplasia who had undergone a duodenocephalo-pancreatectomy. The reason is that he presented upper gastrointestinal obstructive symptoms and the esophagogastroduodenoscopic finding revealed the lesion to be an infiltrating type mass on the second portion of the duodenum with luminal narrowing. An abdominal computed tomography showed a 2.5 cm-sized mass in the duodenal second portion with a suspicious pancreatic invasion and 7 mm-sized lymph node around the duodenum. Duodenocephalopancreatectomy was successfully performed. Histological examination revealed a Brunner's gland hyperplasia. The final diagnosis was the coexistence of Brunner's gland hyperplasia and pancreatic heterotopia with a pancreatic head invasion. The literature on Brunner's gland hyperplasia is reviewed.
布伦纳腺增生是十二指肠的一种良性肿瘤，很少伴有临床症状。我们报告一例64岁患有布伦纳腺增生的男性患者，其接受了十二指肠胰头切除术。原因是他出现了上消化道梗阻症状，食管胃十二指肠镜检查发现病变为十二指肠第二部的浸润型肿物，管腔狭窄。腹部计算机断层扫描显示十二指肠第二部有一个2.5厘米大小的肿物，怀疑有胰腺侵犯，十二指肠周围有一个7毫米大小的淋巴结。成功实施了十二指肠胰头切除术。组织学检查显示为布伦纳腺增生。最终诊断为布伦纳腺增生与胰腺异位并存，并侵犯胰头。本文对布伦纳腺增生的相关文献进行了综述。
