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[骨移植]

[Bone allografting].

作者信息

Katthagen B-D, Prub A

机构信息

Orthopädische Klinik , Klinikum Dortmund gGmbH, Beurhausstrasse 40, 44137, Dortmund.

出版信息

Orthopade. 2008 Aug;37(8):764-71. doi: 10.1007/s00132-008-1272-y.

DOI:10.1007/s00132-008-1272-y
PMID:18584151
Abstract

Bone allografts facilitate bone reconstruction in orthopedic surgery. Appropriate donor selection and processing of grafts minimize the risk of disease transfer. After implantation, bone allografts become necrotic but are incorporated and remodeled in the recipient bone with good regenerative capacity. We use bone allografts in about 3% of all elective orthopedic operations in our hospital. We use bone allografts regularly in acetabuloplasty in cases of severe residual hip dysplasia. These transplants simplify and shorten the operation and improve the results in our hands. Bone allografts are most often used in revision total joint arthroplasty. In cases of reconstruction of defects in benign bone tumors and tumor-like lesions, bone allografts are often suitable. In fibrous dysplasia, corticocancellous bone allografts are even the treatment of choice.

摘要

骨移植有助于骨科手术中的骨重建。合适的供体选择和移植物处理可将疾病传播风险降至最低。植入后,骨移植物会发生坏死,但会在再生能力良好的受体骨中被整合并重塑。在我们医院,约3%的择期骨科手术会使用骨移植。对于严重残留髋关节发育不良的病例,我们在髋臼成形术中常规使用骨移植。在我们手中,这些移植简化并缩短了手术时间,改善了手术效果。骨移植最常用于翻修全关节置换术。在良性骨肿瘤和肿瘤样病变的缺损重建病例中,骨移植通常是合适的。在骨纤维异常增殖症中,皮质松质骨移植甚至是首选治疗方法。

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本文引用的文献

1
Femoral component revision with use of impaction bone-grafting and a cemented polished stem. Surgical technique.使用打压植骨和骨水泥固定抛光柄进行股骨假体翻修。手术技术。
J Bone Joint Surg Am. 2006 Sep;88 Suppl 1 Pt 2:259-74. doi: 10.2106/JBJS.F.00340.
2
[Consequence of European Directive 2004/23/EC for bone banks in Germany].[欧洲指令2004/23/EC对德国骨库的影响]
Orthopade. 2005 Nov;34(11):1160, 1162-6, 1168. doi: 10.1007/s00132-005-0876-8.
3
Infection in massive bone allografts.大块骨移植中的感染
Need, Strategies and Requirements in the Medical System for Bone Banks: A Review Article.
骨库医疗系统中的需求、策略与要求:一篇综述文章
Cureus. 2022 Sep 5;14(9):e28785. doi: 10.7759/cureus.28785. eCollection 2022 Sep.
4
Gelatin Tight-Coated Poly(lactide--glycolide) Scaffold Incorporating rhBMP-2 for Bone Tissue Engineering.用于骨组织工程的含重组人骨形态发生蛋白-2的明胶紧密包被聚(丙交酯-乙交酯)支架
Materials (Basel). 2015 Mar 10;8(3):1009-1026. doi: 10.3390/ma8031009.
5
[What can be done when hip prostheses fail? : New trends in revision endoprosthetics].[髋关节假体失败时该怎么办?:翻修假体的新趋势]
Orthopade. 2011 Dec;40(12):1084-94. doi: 10.1007/s00132-011-1844-0.
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4
Use of structural allografts in acetabular revision surgery.结构异体骨在髋臼翻修手术中的应用。
Clin Orthop Relat Res. 2004 Mar(420):113-21. doi: 10.1097/00003086-200403000-00016.
5
Validation of the 'Marburg bone bank system' for thermodisinfection of allogenic femoral head transplants using selected bacteria, fungi, and spores.使用选定的细菌、真菌和孢子对“马尔堡骨库系统”进行验证,以用于同种异体股骨头移植的热消毒。
Biologicals. 2003 Dec;31(4):287-94. doi: 10.1016/j.biologicals.2003.08.002.
6
Virus inactivation in bone tissue transplants (femoral heads) by moist heat with the 'Marburg bone bank system'.使用“马尔堡骨库系统”通过湿热法对骨组织移植体(股骨头)进行病毒灭活
Biologicals. 2003 Mar;31(1):75-82. doi: 10.1016/s1045-1056(02)00095-7.
7
Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients.重组人骨形态发生蛋白-2治疗开放性胫骨骨折:450例患者的前瞻性、对照、随机研究
J Bone Joint Surg Am. 2002 Dec;84(12):2123-34. doi: 10.2106/00004623-200212000-00001.
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[Surgical reconstruction of fibrous dysplasia of bone in long-term follow-up].[骨纤维异常增殖症的手术重建:长期随访]
Z Orthop Ihre Grenzgeb. 2000 Mar-Apr;138(2):152-8. doi: 10.1055/s-2000-10131.
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Clin Orthop Relat Res. 2000 Feb(371):86-97. doi: 10.1097/00003086-200002000-00010.