Shields Nora, Taylor Nicholas F, Dodd Karen J
Musculoskeletal Research Centre and the School of Physiotherapy, La Trobe University, Melbourne, Australia.
Arch Phys Med Rehabil. 2008 Jul;89(7):1215-20. doi: 10.1016/j.apmr.2007.11.056.
To determine whether progressive resistance training improves muscle strength, muscle endurance, and physical function in adults with Down syndrome.
Single-blind randomized controlled trial.
General community.
Adults (N=20) with Down syndrome (13 men, 7 women; mean age, 26.8+/-7.8 y) were randomly assigned through a concealed allocation block randomized method to either an intervention group (n=9) or a control group (n=11).
The intervention was a supervised, group progressive resistance training program, consisting of 6 exercises using weight machines performed twice a week for 10 weeks. Participants completed 2 to 3 sets of between 10 to 12 repetitions of each exercise until they reached fatigue. The control group continued with their usual activities.
The outcomes measured by blinded assessors were muscle strength (1-repetition maximum [1-RM]), muscle endurance (number of repetitions at 50% of 1-RM) for chest press and leg press, timed stairs test, and the grocery shelving task.
The intervention group showed significant improvement in upper-limb muscle endurance compared with the control group (mean difference in the number of repetitions of the chest press at 50% of 1-RM was 16.7, 95% confidence interval, [CI] 7.1-26.2); and a trend toward an improvement in upper-limb muscle strength (mean difference in chest press 1-RM, 8.6 kg; 95% CI, -1.3 to 18.5 kg) and in upper-limb function (mean difference in grocery shelving task, -20.3s; 95% CI, -45.7 to 5.2s). There were no significant differences between the groups for lower-limb muscle performance or physical function measures. No major adverse events for the intervention were noted.
Progressive resistance training is a safe and feasible fitness option that can improve upper-limb muscle endurance in adults with Down syndrome (ACTR identifier ACTRN 012606000515594.).
确定渐进性抗阻训练是否能改善唐氏综合征成年人的肌肉力量、肌肉耐力和身体功能。
单盲随机对照试验。
普通社区。
20名唐氏综合征成年人（13名男性，7名女性；平均年龄26.8±7.8岁）通过隐蔽分配区组随机法随机分为干预组（n = 9）或对照组（n = 11）。
干预措施为一项有监督的团体渐进性抗阻训练计划，包括使用重量训练器械进行6项练习，每周进行2次，共10周。参与者完成每项练习10至12次重复的2至3组，直至疲劳。对照组继续其日常活动。
由盲法评估者测量的结果包括肌肉力量（1次重复最大值[1-RM]）、卧推和腿举的肌肉耐力（1-RM的50%时的重复次数）、定时楼梯测试以及杂货店货架整理任务。
与对照组相比，干预组上肢肌肉耐力有显著改善（1-RM的50%时卧推重复次数的平均差异为16.7，95%置信区间[CI] 7.1 - 26.2）；上肢肌肉力量有改善趋势（卧推1-RM的平均差异为8.6 kg；95% CI，-1.3至18.5 kg）以及上肢功能有改善趋势（杂货店货架整理任务的平均差异为-20.3秒；95% CI，-45.7至5.2秒）。两组在下肢肌肉表现或身体功能测量方面无显著差异。未观察到干预的重大不良事件。
渐进性抗阻训练是一种安全可行的健身选择，可改善唐氏综合征成年人的上肢肌肉耐力（澳大利亚临床试验注册号ACTRN 012606000515594）。
