Suppr超能文献

腹腔镜可调节胃束带治疗病态肥胖症的预后预测因素:380例患者的前瞻性研究结果

Predictors of outcome in treatment of morbid obesity by laparoscopic adjustable gastric banding: results of a prospective study of 380 patients.

作者信息

Wölnerhanssen Bettina K, Peters Thomas, Kern Beatrice, Schötzau Andy, Ackermann Christoph, von Flüe Markus, Peterli Ralph

机构信息

Department of Surgery, St. Claraspital, Kleinriehenstrasse 30, Basel, Switzerland.

出版信息

Surg Obes Relat Dis. 2008 Jul-Aug;4(4):500-6. doi: 10.1016/j.soard.2008.03.252. Epub 2008 Jun 30.

Abstract

BACKGROUND

We investigated the outcome predictors of laparoscopic gastric banding (LAGB) for morbidly obese patients.

METHODS

From December 1996 to November 2004, a total of 380 consecutive unselected patients (78% female; median age 40 yr, range 17-66; body mass index 44.3 kg/m(2), range 35-75) were prospectively evaluated and underwent LAGB. The follow-up rate after a median of 5 years (range 1.5-9.4) was 98%. A survival model was applied, and a multivariate Cox proportional hazard model was used to calculate the hazard ratios for the influential factors.

RESULTS

Of the 380 patients, 128 (33.7%) had their bands removed. Of these 128 patients, 2.4% declined another operation, 18.2% underwent biliopancreatic diversion with duodenal switch, 7.1% underwent laparoscopic Roux-en-Y gastric bypass, and 6% underwent laparoscopic sleeve gastrectomy. The excess weight loss of the remaining 252 patients (66.3%) with a band in situ (including 21 patients after rebanding) was 40%, and only 25% reached an excess weight loss >50%. Older age, binge eating disorder, and sweet-eating behavior were predictors of a poor outcome after LAGB. In contrast, sex, primary body mass index, and co-morbidities had no influence on outcome.

CONCLUSION

LAGB was less successful in older patients and in patients with binge eating disorder or sweet-eating behavior. These patients might be candidates for a different bariatric procedure.

摘要

背景

我们研究了腹腔镜胃束带术(LAGB)治疗病态肥胖患者的预后预测因素。

方法

从1996年12月至2004年11月,对380例未经选择的连续患者(78%为女性;中位年龄40岁,范围17 - 66岁;体重指数44.3 kg/m²,范围35 - 75)进行前瞻性评估并接受LAGB。中位随访5年(范围1.5 - 9.4年)后的随访率为98%。应用生存模型,并使用多变量Cox比例风险模型计算影响因素的风险比。

结果

380例患者中,128例(33.7%)移除了束带。在这128例患者中,2.4%拒绝再次手术,18.2%接受了胆胰转流十二指肠转位术,7.1%接受了腹腔镜Roux - en - Y胃旁路术,6%接受了腹腔镜袖状胃切除术。其余252例(66.3%)束带在位的患者(包括21例重新束带后的患者)的超重减轻率为40%,只有25%的患者超重减轻率>50%。年龄较大、暴饮暴食症和爱吃甜食的行为是LAGB术后预后不良的预测因素。相比之下,性别、初始体重指数和合并症对预后无影响。

结论

LAGB在老年患者以及患有暴饮暴食症或爱吃甜食行为的患者中成功率较低。这些患者可能是不同减重手术的候选者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验