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术前体重减轻并不预测腹腔镜可调节胃束带减重术后的体重减轻。

Pre-operative weight loss does not predict weight loss following laparoscopic adjustable gastric banding.

机构信息

Centre for Obesity Research and Education, Monash University, Level 6, 99 Commercial Road, Melbourne, 3004, Australia,

出版信息

Obes Surg. 2013 Oct;23(10):1611-5. doi: 10.1007/s11695-013-0974-3.

Abstract

BACKGROUND

This study aimed to test the hypothesis that the amount of weight lost on a mandatory 2-week pre-operative very-low-calorie diet (VLCD) would predict the longer-term outcomes of laparoscopic adjustable gastric banding (LAGB).

METHODS

All patients treated with a primary LAGB from 21 October 2008 until 30 June 2010, who were prescribed a 2-week pre-operative VLCD, have been included in the study. Patient age, weight, BMI and excess weight (defined as weight above a BMI of 25) were extracted on the day of first visit, day of surgery and at the post-operative visits at 3, 12 and 24 months. From these data, percent excess weight loss (EWL) was calculated and compared at all time points.

RESULTS

The weight loss achieved on a mandatory 2-week pre-operative diet did not predict weight outcomes at 2 years (r = -0.008; p = 0.931). Using multivariate analysis, the best predictor of 24-month percent EWL was percent EWL at 3 months post operation (sr(2) = 0.34; p = 0.003).

CONCLUSIONS

Results from a pre-operative diet should not be used to predict the ultimate outcome of bariatric surgery. The weight loss at 3 months following LAGB was a strong predictor of longer-term outcomes. There may be potential for improving longer-term results with LAGB by better supporting patients who are not achieving good weight loss at this early time point.

摘要

背景

本研究旨在检验一个假设,即强制性 2 周术前极低热量饮食(VLCD)减轻的体重量将预测腹腔镜可调节胃束带术(LAGB)的长期结果。

方法

所有于 2008 年 10 月 21 日至 2010 年 6 月 30 日接受初次 LAGB 治疗且被规定进行 2 周术前 VLCD 的患者均被纳入研究。在首次就诊日、手术日以及术后 3、12 和 24 个月的就诊日,提取患者年龄、体重、BMI 和超重(定义为 BMI 高于 25 的体重)。从这些数据中计算并比较所有时间点的超重百分比体重减轻(EWL)。

结果

强制性 2 周术前饮食所实现的体重减轻并不能预测 2 年时的体重结果(r=−0.008;p=0.931)。使用多元分析,24 个月时的 EWL 百分比的最佳预测指标是术后 3 个月时的 EWL 百分比(sr(2)=0.34;p=0.003)。

结论

术前饮食的结果不应用于预测减重手术的最终结果。LAGB 术后 3 个月的体重减轻是长期结果的有力预测指标。通过更好地支持在这个早期时间点没有实现良好体重减轻的患者,可能会提高 LAGB 的长期结果。

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