Centre for Obesity Research and Education, Monash University, Level 6, 99 Commercial Road, Melbourne, 3004, Australia,
Obes Surg. 2013 Oct;23(10):1611-5. doi: 10.1007/s11695-013-0974-3.
This study aimed to test the hypothesis that the amount of weight lost on a mandatory 2-week pre-operative very-low-calorie diet (VLCD) would predict the longer-term outcomes of laparoscopic adjustable gastric banding (LAGB).
All patients treated with a primary LAGB from 21 October 2008 until 30 June 2010, who were prescribed a 2-week pre-operative VLCD, have been included in the study. Patient age, weight, BMI and excess weight (defined as weight above a BMI of 25) were extracted on the day of first visit, day of surgery and at the post-operative visits at 3, 12 and 24 months. From these data, percent excess weight loss (EWL) was calculated and compared at all time points.
The weight loss achieved on a mandatory 2-week pre-operative diet did not predict weight outcomes at 2 years (r = -0.008; p = 0.931). Using multivariate analysis, the best predictor of 24-month percent EWL was percent EWL at 3 months post operation (sr(2) = 0.34; p = 0.003).
Results from a pre-operative diet should not be used to predict the ultimate outcome of bariatric surgery. The weight loss at 3 months following LAGB was a strong predictor of longer-term outcomes. There may be potential for improving longer-term results with LAGB by better supporting patients who are not achieving good weight loss at this early time point.
本研究旨在检验一个假设,即强制性 2 周术前极低热量饮食(VLCD)减轻的体重量将预测腹腔镜可调节胃束带术(LAGB)的长期结果。
所有于 2008 年 10 月 21 日至 2010 年 6 月 30 日接受初次 LAGB 治疗且被规定进行 2 周术前 VLCD 的患者均被纳入研究。在首次就诊日、手术日以及术后 3、12 和 24 个月的就诊日,提取患者年龄、体重、BMI 和超重(定义为 BMI 高于 25 的体重)。从这些数据中计算并比较所有时间点的超重百分比体重减轻(EWL)。
强制性 2 周术前饮食所实现的体重减轻并不能预测 2 年时的体重结果(r=−0.008;p=0.931)。使用多元分析,24 个月时的 EWL 百分比的最佳预测指标是术后 3 个月时的 EWL 百分比(sr(2)=0.34;p=0.003)。
术前饮食的结果不应用于预测减重手术的最终结果。LAGB 术后 3 个月的体重减轻是长期结果的有力预测指标。通过更好地支持在这个早期时间点没有实现良好体重减轻的患者,可能会提高 LAGB 的长期结果。