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美国绝经后女性皮下脂肪组织和饮食中的脂肪酸组成

Fatty acid composition of subcutaneous adipose tissue and diet in postmenopausal US women.

作者信息

London S J, Sacks F M, Caesar J, Stampfer M J, Siguel E, Willett W C

机构信息

Department of Preventive Medicine, University of Southern California Medical School, Los Angeles 90033.

出版信息

Am J Clin Nutr. 1991 Aug;54(2):340-5. doi: 10.1093/ajcn/54.2.340.

DOI:10.1093/ajcn/54.2.340
PMID:1858698
Abstract

The distributions of fatty acids in subcutaneous-adipose-tissue aspirates and their relation to intake as assessed by a semiquantitative food-frequency questionnaire were investigated in 115 postmenopausal US women free from cancer. Percentages of fatty acids in adipose tissue were significantly correlated with the percentage of total fat intake for polyunsaturated fatty acids (Spearman correlation = 0.37), n-3 fatty acids of marine origin (Spearman correlation = 0.48), and trans fatty acids (Spearman correlation = 0.51) but not for saturated and monounsaturated fatty acids. Correlations were somewhat stronger in 78 women with stable weight over the 6 mo before fat aspiration. These data suggest that intakes of polyunsaturated fatty acids, including n-3 fatty acids, and trans fatty acids are reflected in the adipose tissue but that intakes of saturated and monounsaturated fatty acids are not. The data also provide further support for the validity of the food-frequency questionnaire in the assessment of fat intake.

摘要

对115名无癌症的美国绝经后女性进行了研究,调查皮下脂肪抽吸物中脂肪酸的分布及其与通过半定量食物频率问卷评估的摄入量之间的关系。脂肪组织中脂肪酸的百分比与多不饱和脂肪酸(斯皮尔曼相关性=0.37)、海洋来源的n-3脂肪酸(斯皮尔曼相关性=0.48)和反式脂肪酸(斯皮尔曼相关性=0.51)的总脂肪摄入量百分比显著相关,但与饱和脂肪酸和单不饱和脂肪酸无关。在抽脂前6个月体重稳定的78名女性中,相关性略强。这些数据表明,包括n-3脂肪酸在内的多不饱和脂肪酸和反式脂肪酸的摄入量在脂肪组织中有所体现,但饱和脂肪酸和单不饱和脂肪酸的摄入量则不然。这些数据还为食物频率问卷在评估脂肪摄入量方面的有效性提供了进一步支持。

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