Korytovskaia M A, Sarkisian N I, Tishman M I, Ulanova I N
Klin Med (Mosk). 2008;86(5):64-5.
Simple eosinophilic pneumonia (Luffler's syndrome) is combination of "volatile" infiltrates, independently passing during one month and detecting only in chest organs roentgenography; often pass symptomless. There is a mild eosinophilia in the blood. Acute eosinophilic pneumonia is an antipode of simple eosinophilic pneumonia, has a clinical course with acute respiratory failure, pulmonary destruction, high eosinophilia and favorable prognosis under conditions of treatment with glucocorticoids. In chronic eosinophilic pneumonia infiltrates in the lungs recur more than 4 weeks; the disease has a course with fever, intoxication, high eosinophilia and pleural effusion. The special feature of this clinical case is a combination some symptoms of all kinds of eosinophilic pneumonia. Equally with symptomless course, normal number of eosinophils, there is an absence of tendency to spontaneous recovery, presence of pulmonary infiltrates up to therapy with glucocorticoids; non-typical roentgenological picture of chest organs in the beginning of disease.
单纯性嗜酸性粒细胞性肺炎(吕弗勒综合征)是“游走性”浸润的组合,在一个月内自行消散,仅在胸部器官X线检查时发现;通常无症状。血液中存在轻度嗜酸性粒细胞增多。急性嗜酸性粒细胞性肺炎是单纯性嗜酸性粒细胞性肺炎的对立面,其临床过程伴有急性呼吸衰竭、肺组织破坏、嗜酸性粒细胞增多明显,在使用糖皮质激素治疗的情况下预后良好。在慢性嗜酸性粒细胞性肺炎中,肺部浸润持续超过4周;该病病程伴有发热、中毒症状、嗜酸性粒细胞增多明显及胸腔积液。该临床病例的特点是兼具各类嗜酸性粒细胞性肺炎的一些症状。与无症状病程、嗜酸性粒细胞数量正常一样,不存在自发恢复的倾向,在使用糖皮质激素治疗前存在肺部浸润;疾病初期胸部器官的X线表现不典型。