[利用电喷雾电离质谱法对草乌叶提取物中生物碱类活性成分进行比对的研究]
[Study on active components alignment of alkaloids in extractive of Folium aconiti kusnezoffii by ESI-MS].
作者信息
Tu Ya, Zhang Gui-Jun, Wang Shu-Min, Liu Zhi-Qiang
机构信息
School of Chinese Pharmacology, Beijing University of Chinese Medicine, Beijing 100102, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2008 Apr;33(7):789-90.
OBJECTIVE
To analyze the active components alignment of aconitum alkaloids on extractive of Folium Aconiti Kusnezoffii and its decoction.
METHOD
The analysis was performed by the method of ESI-MS.
RESULT
The biester-type and the triester-type diterpenoid aconitum alkaloids were hydrolysed after boiling in water, the former was hydrolyzed to 14-benzoylaconine and aconine, the latter to 3-acylaconine.
CONCLUSION
The method is simple rapid and sensitive, provide a new instrumentality to analyze the active components alignment of aconitum alkaloids on extractive of folium aconiti kusnezoffii.
目的
分析乌头生物碱在北乌头叶提取物及其汤剂中的活性成分排列。
方法
采用电喷雾质谱法进行分析。
结果
双酯型和三酯型二萜类乌头生物碱在水中煮沸后水解，前者水解为14-苯甲酰乌头原碱和乌头原碱，后者水解为3-酰基乌头原碱。
结论
该方法简便、快速、灵敏，为分析乌头生物碱在北乌头叶提取物中的活性成分排列提供了一种新手段。
Zotero 插件