Farias Sarah Tomaszewski, Mungas Dan, Reed Bruce R, Cahn-Weiner Deborah, Jagust William, Baynes Kathleen, Decarli Charles
Department of Neurology, University of California, CA 95817, USA.
Neuropsychology. 2008 Jul;22(4):531-44. doi: 10.1037/0894-4105.22.4.531.
This article describes the development and validation of an instrument to assess cognitively mediated functional abilities in older adults, Everyday Cognition (ECog). The ECog is an informant-rated questionnaire comprised of multiple subscales. Confirmatory factor analysis (CFA) was used to examine its factor structure. Convergent validity was evaluated by comparing it to established measures of everyday function. External validity was evaluated by comparing ECog results across different clinical groups [cognitively normal, mild cognitive impairment (MCI), dementia]. CFA supported a seven-factor model including one global factor and six domain-specific factors (Everyday Memory, Language, Visuospatial Abilities, Planning, Organization, and Divided attention). The ECog correlated with established measures of functional status and global cognition, but only weakly with age and education. The clinical groups performed differently in each domain. In addition to the global factor, the Everyday Memory factor independently differentiated MCI from Normal, while the Everyday Language domain differentiated Dementia from MCI. Different subtypes of MCI also showed different patterns. Results suggest the ECog shows promise as a useful tool for the measurement of general and domain-specific everyday functions in the elderly.
本文介绍了一种用于评估老年人认知介导功能能力的工具——日常认知(ECog)的开发与验证。ECog是一份由多分量表组成的他人评定问卷。采用验证性因素分析(CFA)来检验其因素结构。通过将其与已有的日常功能测量方法进行比较来评估收敛效度。通过比较不同临床组[认知正常、轻度认知障碍(MCI)、痴呆]的ECog结果来评估外部效度。CFA支持一个七因素模型,包括一个总体因素和六个特定领域因素(日常记忆、语言、视觉空间能力、计划、组织和分散注意力)。ECog与已有的功能状态和总体认知测量方法相关,但与年龄和教育程度的相关性较弱。各临床组在每个领域的表现不同。除总体因素外,日常记忆因素可独立区分MCI与正常组,而日常语言领域可区分痴呆与MCI。不同亚型的MCI也表现出不同的模式。结果表明,ECog有望成为测量老年人一般和特定领域日常功能的有用工具。