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验证韩国日常认知测试(K-ECog)。

Validation of the Korean-Everyday Cognition (K-ECog).

机构信息

Department of Psychology, College of Social Sciences, Hallym University, Chuncheon, Korea.

Department of Neurology, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea.

出版信息

J Korean Med Sci. 2019 Feb 27;34(9):e67. doi: 10.3346/jkms.2019.34.e67. eCollection 2019 Mar 11.

DOI:10.3346/jkms.2019.34.e67
PMID:30863265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6406041/
Abstract

BACKGROUND

In the early diagnosis of dementia, an important factor is the evaluation of activities of daily living. The Everyday Cognition (ECog) scale was developed to measure functional changes that are the everyday correlates of specific neuropsychological impairments. This study aimed to examine the validity of the Korean version of Everyday Cognition (K-ECog).

METHODS

The participants were 268 cognitively normal older adults (NA), 151 amnestic mild cognitive impairment (aMCI), and 77 dementia of the Alzheimer's type (DAT). The Korean-Mini Mental State Examination (K-MMSE), Korean-Montreal Cognitive Assessment (K-MoCA), and Short form of the Geriatric Depression Scale (SGDS) were administered to all the participants. The K-ECog and Korean-Instrumental Activities of Daily Living (K-IADL) were rated by their informants.

RESULTS

Internal consistency (Cronbach's α) of K-ECog global function was 0.93, and its test-retest reliability (Pearson's ) was 0.73. K-ECog was significantly correlated with K-IADL (0.66), K-MMSE (-0.38), and K-MoCA (-0.26). Confirmatory factor analysis of K-ECog yielded seven factor model that the original ECog proposed. K-ECog global score and six domain scores were significantly different across the NA, aMCI, and DAT groups. Receiver operating characteristic curve analyses showed that K-ECog effectively differentiated aMCI and DAT patients from NA, suggesting that K-ECog is as sensitive for detecting functional impairments as K-IADL. The proposed optimal cut-off score to differentiate aMCI from NA was 1.41.

CONCLUSION

K-ECog is proven reliable and valid for clinical use. K-ECog can be used to distinguish very early stages of impaired ADL and cognitive impairment in the community.

摘要

背景

在痴呆症的早期诊断中,评估日常生活活动是一个重要因素。日常认知(ECog)量表的开发是为了衡量与特定神经心理损伤相关的日常功能变化。本研究旨在检验韩国版日常认知(K-ECog)的有效性。

方法

参与者包括 268 名认知正常的老年人(NA)、151 名遗忘型轻度认知障碍(aMCI)和 77 名阿尔茨海默病型痴呆(DAT)患者。所有参与者均接受了韩国简易精神状态检查(K-MMSE)、韩国蒙特利尔认知评估(K-MoCA)和老年抑郁量表短表(SGDS)的测试。其知情人对 K-ECog 和韩国日常生活活动工具(K-IADL)进行了评分。

结果

K-ECog 总体功能的内部一致性(Cronbach's α)为 0.93,其重测信度(Pearson's )为 0.73。K-ECog 与 K-IADL(0.66)、K-MMSE(-0.38)和 K-MoCA(-0.26)显著相关。K-ECog 的验证性因子分析得出了与原始 ECog 提出的七个因素模型。K-ECog 总分和六个领域得分在 NA、aMCI 和 DAT 组之间存在显著差异。受试者工作特征曲线分析表明,K-ECog 能够有效区分 aMCI 和 DAT 患者与 NA,表明 K-ECog 与 K-IADL 一样敏感,能够检测到功能障碍。将 aMCI 与 NA 区分开来的最佳截断值为 1.41。

结论

K-ECog 具有可靠且有效的临床应用价值。K-ECog 可用于区分社区中认知和日常生活活动能力受损的早期阶段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4c5/6406041/d11fbeb619a8/jkms-34-e67-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4c5/6406041/c66faa8fbfe4/jkms-34-e67-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4c5/6406041/2d3ffdbf56dd/jkms-34-e67-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4c5/6406041/d11fbeb619a8/jkms-34-e67-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4c5/6406041/c66faa8fbfe4/jkms-34-e67-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4c5/6406041/2d3ffdbf56dd/jkms-34-e67-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4c5/6406041/d11fbeb619a8/jkms-34-e67-g003.jpg

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