Kadowaki Toru, Hamada Hironobu, Miyoshi Seigo, Hamaguchi Naohiko, Sakai Kimiko, Ito Ryoji, Yasutake-Oshima Miki, Higaki Jitsuo, Kito Katsumi
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon, Japan.
Intern Med. 2008;47(13):1251-4. doi: 10.2169/internalmedicine.47.0823. Epub 2008 Jul 1.
An unusual case of refractory pneumothorax secondary to lung cancer in a 69-year-old man patient with idiopathic pulmonary fibrosis (IPF) is described. High-pressure suction applied through chest tube did not resolve the large right pneumothorax. Acute exacerbation of IPF has also appeared. Respiratory state worsened acutely, and the patient died on the fifth hospital day. In the present case, the large right pneumothorax was initially thought to be associated with IPF because pneumothorax is common in patients with IPF. However, postmortem microscopic examination revealed that the refractory pneumothorax was secondary to perforation of the pleura due to a necrotic peripheral lung cancer.
本文描述了一例69岁患有特发性肺纤维化（IPF）的男性患者，因肺癌继发难治性气胸的罕见病例。通过胸管进行的高压抽吸未能消除右侧大量气胸。IPF还出现了急性加重。患者呼吸状态急剧恶化，于住院第五天死亡。在本病例中，最初认为右侧大量气胸与IPF有关，因为气胸在IPF患者中很常见。然而，尸检显微镜检查显示，难治性气胸是由坏死性周围型肺癌导致的胸膜穿孔所致。
