肝纤维化发病机制与诊断的最新进展 - Suppr

Recent advances in the pathogenesis and diagnosis of liver fibrosis.

作者信息

Török Natalie J

机构信息

Department of Internal Medicine, Division of Gastroenterology and Hepatology, UC Davis Medical Center, 4150, V Street Sacramento, CA 95817, USA.

出版信息

J Gastroenterol. 2008;43(5):315-21. doi: 10.1007/s00535-008-2181-x. Epub 2008 Jul 1.

DOI:10.1007/s00535-008-2181-x

PMID:18592147

Abstract

摘要

相似文献

Recent advances in the pathogenesis and diagnosis of liver fibrosis.肝纤维化发病机制与诊断的最新进展

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Liver stiffness measurement in combination with noninvasive markers for the improved diagnosis of B-viral liver cirrhosis.结合非侵入性标志物进行肝脏硬度测量以改善B型病毒性肝硬化的诊断

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Non-invasive assessment of liver fibrosis with impulse elastography: comparison of Supersonic Shear Imaging with ARFI and FibroScan®.超声剪切波弹性成像技术与 FibroScan®对肝纤维化的无创评估：比较研究。

J Hepatol. 2014 Sep;61(3):550-7. doi: 10.1016/j.jhep.2014.04.044. Epub 2014 May 9.

Anti-fibrotic potential of human umbilical cord mononuclear cells and mouse bone marrow cells in CCl- induced liver fibrosis in mice.人脐带间充质干细胞和小鼠骨髓细胞抗肝纤维化作用及其机制的研究。

Biomed Pharmacother. 2017 May;89:1378-1386. doi: 10.1016/j.biopha.2017.03.007. Epub 2017 Mar 19.

Liver fibrosis and chronic viral hepatitis.肝纤维化与慢性病毒性肝炎

Arch Med Res. 2007 Aug;38(6):644-51. doi: 10.1016/j.arcmed.2006.10.001.

High aspartate to alanine aminotransferase ratio is an indicator of cirrhosis and poor outcome in patients with primary sclerosing cholangitis.天冬氨酸氨基转移酶与丙氨酸氨基转移酶比值升高是原发性硬化性胆管炎患者肝硬化及预后不良的一项指标。

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Raf Kinase Inhibitory Protein Down-Expression Exacerbates Hepatic Fibrosis In Vivo and In Vitro.Raf激酶抑制蛋白表达下调在体内和体外均加剧肝纤维化。

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Optimization of hepatitis B cirrhosis detection by stepwise application of transient elastography and routine biomarkers.通过逐步应用瞬时弹性成像和常规生物标志物优化乙型肝炎肝硬化检测

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Noninvasive estimation of fibrosis progression overtime using the FIB-4 index in chronic hepatitis C.使用 FIB-4 指数无创性评估慢性丙型肝炎纤维化进展。

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Ameliorative effects of tannic acid on carbon tetrachloride-induced liver fibrosis in vivo and in vitro.单宁酸对四氯化碳诱导的体内外肝纤维化的改善作用。

J Pharmacol Sci. 2016 Jan;130(1):15-23. doi: 10.1016/j.jphs.2015.12.002. Epub 2015 Dec 15.

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Multiple Roles of Black Raspberry Anthocyanins Protecting against Alcoholic Liver Disease.黑覆盆子花色苷在防治酒精性肝病中的多重作用

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TGF-β induces liver fibrosis via miRNA-181a-mediated down regulation of augmenter of liver regeneration in hepatic stellate cells.TGF-β 通过 miRNA-181a 介导的肝星状细胞中肝再生增强因子的下调诱导肝纤维化。

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Betulinic acid attenuates liver fibrosis by inducing autophagy via the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.桦木酸通过丝裂原活化蛋白激酶/细胞外信号调节激酶通路诱导自噬来减轻肝纤维化。

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Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies.利拉鲁肽改善肝硬化肝脏微血管功能障碍：转化研究证据。

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Cancer-associated fibroblasts in hepatocellular carcinoma.肝细胞癌中的癌症相关成纤维细胞

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Chronic hepatitis C virus infection: Serum biomarkers in predicting liver damage.慢性丙型肝炎病毒感染：预测肝损伤的血清生物标志物

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本文引用的文献

Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver.肝星状细胞：肝脏中具有多种形态、多功能且神秘的细胞。

Physiol Rev. 2008 Jan;88(1):125-72. doi: 10.1152/physrev.00013.2007.

Assessment of graft fibrosis by transient elastography in patients with recurrent hepatitis C after living donor liver transplantation.活体肝移植术后丙型肝炎复发患者通过瞬时弹性成像评估移植肝纤维化情况。

Transplantation. 2008 Jan 15;85(1):69-74. doi: 10.1097/01.tp.0000297248.18483.16.

Relationship of serum fibrosis markers with liver fibrosis stage and collagen content in patients with advanced chronic hepatitis C.晚期慢性丙型肝炎患者血清纤维化标志物与肝纤维化分期及胶原含量的关系

Hepatology. 2008 Mar;47(3):789-98. doi: 10.1002/hep.22099.

Magnetic resonance imaging of hepatic fibrosis: emerging clinical applications.肝纤维化的磁共振成像：新兴的临床应用

Hepatology. 2008 Jan;47(1):332-42. doi: 10.1002/hep.21972.

Cellular and molecular mechanisms of fibrosis.纤维化的细胞和分子机制。

J Pathol. 2008 Jan;214(2):199-210. doi: 10.1002/path.2277.

Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage.瞬时弹性成像在检测急性肝损伤患者的肝硬化方面不可靠。

Hepatology. 2008 Feb;47(2):592-5. doi: 10.1002/hep.22056.

Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes.转化生长因子-β通过下调成年大鼠肝细胞中claudin-1的表达和栅栏功能诱导上皮-间质转化。

Liver Int. 2008 Apr;28(4):534-45. doi: 10.1111/j.1478-3231.2007.01631.x. Epub 2007 Nov 21.

TLR4 enhances TGF-beta signaling and hepatic fibrosis.Toll样受体4（TLR4）增强转化生长因子-β（TGF-β）信号传导及肝纤维化。

Nat Med. 2007 Nov;13(11):1324-32. doi: 10.1038/nm1663. Epub 2007 Oct 21.

Assessment of hepatic fibrosis with magnetic resonance elastography.磁共振弹性成像评估肝纤维化

Clin Gastroenterol Hepatol. 2007 Oct;5(10):1207-1213.e2. doi: 10.1016/j.cgh.2007.06.012.

Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9.凋亡肝细胞DNA通过Toll样受体9抑制肝星状细胞趋化性。

Hepatology. 2007 Nov;46(5):1509-18. doi: 10.1002/hep.21867.

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Recent advances in the pathogenesis and diagnosis of liver fibrosis.

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