Baskin Darrell E, Reddy Ashvini K, Chu Yvonne I, Coats David K
Department of Ophthalmology, Baylor College of Medicine Texas Children's Hospital, Houston, Texas, USA.
J AAPOS. 2008 Oct;12(5):456-9. doi: 10.1016/j.jaapos.2008.04.006. Epub 2008 Jul 2.
To report (1) the prevalence of bacteremia among infants with dacryocystitis and (2) the influence of timing of antibiotic administration on the need for repeat probing in the management of these patients.
A retrospective analysis of the hospital records of 25 infants < or =6 weeks of age treated for acute dacryocystitis was conducted, including analysis of laboratory data and outcomes.
Of 22 infants who underwent blood cultures, 5 (22.7%) were bacteremic. Twenty-one of the 25 infants underwent nasolacrimal duct probing. Infants who received preoperative antibiotics were less likely to require a repeat probing than those who did not (6% vs. 80%), and this difference was statistically significant (p = 0.004).
The high rate of bacteremia in this series of patients and the significantly lower incidence of repeat probing among infants who received preprocedural antibiotics suggests that blood cultures and subsequent administration of intravenous antibiotics should be considered prior to probing of infants with dacryocystitis.
报告(1)泪囊炎婴儿中菌血症的患病率,以及(2)抗生素给药时机对这些患者治疗中重复探通需求的影响。
对25例年龄≤6周的急性泪囊炎婴儿的医院记录进行回顾性分析,包括实验室数据和治疗结果分析。
在接受血培养的22例婴儿中,5例(22.7%)发生菌血症。25例婴儿中有21例行鼻泪管探通术。接受术前抗生素治疗的婴儿比未接受者需要重复探通的可能性更小(6% 对80%),且这种差异具有统计学意义(p = 0.004)。
该系列患者中菌血症发生率高,且接受术前抗生素治疗的婴儿重复探通发生率显著更低,这表明对于泪囊炎婴儿,在探通术前应考虑进行血培养并随后给予静脉抗生素治疗。