Daniels Stephen R, Greer Frank R
Pediatrics. 2008 Jul;122(1):198-208. doi: 10.1542/peds.2008-1349.
This clinical report replaces the 1998 policy statement from the American Academy of Pediatrics on cholesterol in childhood, which has been retired. This report has taken on new urgency given the current epidemic of childhood obesity with the subsequent increasing risk of type 2 diabetes mellitus, hypertension, and cardiovascular disease in older children and adults. The approach to screening children and adolescents with a fasting lipid profile remains a targeted approach. Overweight children belong to a special risk category of children and are in need of cholesterol screening regardless of family history or other risk factors. This report reemphasizes the need for prevention of cardiovascular disease by following Dietary Guidelines for Americans and increasing physical activity and also includes a review of the pharmacologic agents and indications for treating dyslipidemia in children.
本临床报告取代了美国儿科学会1998年发布的关于儿童胆固醇的政策声明,该声明现已废止。鉴于当前儿童肥胖流行,以及随之而来的大龄儿童和成人患2型糖尿病、高血压和心血管疾病风险增加的情况,本报告具有了新的紧迫性。对儿童和青少年进行空腹血脂筛查的方法仍然是一种有针对性的方法。超重儿童属于特殊的高危儿童类别,无论家族病史或其他风险因素如何,都需要进行胆固醇筛查。本报告再次强调,应遵循《美国膳食指南》并增加体育活动以预防心血管疾病,还包括对治疗儿童血脂异常的药物和适应症的综述。