头状葡萄球菌血流分离株中的万古霉素异质性耐药
Vancomycin heteroresistance in bloodstream isolates of Staphylococcus capitis.
作者信息
D'mello Danaë, Daley Andrew J, Rahman Muhammad Shihab, Qu Yue, Garland Suzanne, Pearce Christopher, Deighton Margaret A
机构信息
School of Applied Sciences, RMIT University, Plenty Road, Bundoora, Victoria, Australia.
出版信息
J Clin Microbiol. 2008 Sep;46(9):3124-6. doi: 10.1128/JCM.00592-08. Epub 2008 Jul 2.
Abstract
Nine Staphylococcus capitis isolates from blood cultures of newborns were examined for resistance to vancomycin. MICs were within the susceptible range, but population profiling revealed a resistant subpopulation. Only isolates with the largest subpopulation were identified as heteroresistant to vancomycin by Etest. This finding may have therapeutic implications.
摘要
对从新生儿血培养物中分离出的9株头状葡萄球菌进行了万古霉素耐药性检测。最低抑菌浓度（MIC）在敏感范围内，但群体分析显示存在耐药亚群。只有亚群最大的分离株通过Etest法被鉴定为对万古霉素异质性耐药。这一发现可能具有治疗意义。
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