在单侧内嗅皮层损伤后，神经节苷脂治疗的大鼠学习交替行为的恢复增强。

Enhanced recovery of learned alternation in ganglioside-treated rats after unilateral entorhinal lesions.

作者信息

Ramirez J J, Fass-Holmes B, Karpiak S E, Harshbarger R, Zengel D, Wright P, Valbuena M

机构信息

Department of Psychology, Davidson College, NC 28036.

出版信息

Behav Brain Res. 1991 Apr 18;43(1):99-101. doi: 10.1016/s0166-4328(05)80057-9.

DOI:10.1016/s0166-4328(05)80057-9

PMID:1859620

Abstract

The present study demonstrates that an abbreviated regimen of ganglioside treatments attenuates the behavioral impairments produced by unilateral lesions of the entorhinal cortex. Ganglioside treatments not only accelerate recovery of learned alternation on a Y-maze, but also reduce total errors and perseverative errors.

摘要

本研究表明，神经节苷脂治疗的简化方案可减轻内嗅皮质单侧损伤所产生的行为障碍。神经节苷脂治疗不仅能加速Y迷宫上习得性交替的恢复，还能减少总错误和持续性错误。