Patanè Salvatore, Marte Filippo
Int J Cardiol. 2009 Jun 26;135(2):e44-6. doi: 10.1016/j.ijcard.2008.03.072. Epub 2008 Jul 1.
The discovery of a left ventricular mass obliges the clinician to perform a differential diagnosis including tumour or lipoma versus thrombus and its assessment presents important clinical implications. Dilated cardiomyopathy has been associated with left ventricular thrombosis which leads to substantial morbidity and mortality as a site for peripheral emboli. There are some studies on patients with dilated cardiomyopathy showing altered hemostasis and platelet behavior despite sinus rhythm. An increased incidence of thromboembolism is also well recognized in patients with left ventricular systolic dysfunction complicating history of myocardial infarction. Clinical dilemmas in treating left ventricular thrombus have been described too. We present a case of a large mobile left ventricular thrombus in a 71-year-old Italian man with dilated cardiomyopathy and history of myocardial infarction.
发现左心室肿块后,临床医生必须进行鉴别诊断,包括肿瘤或脂肪瘤与血栓的鉴别,其评估具有重要的临床意义。扩张型心肌病与左心室血栓形成有关,左心室血栓作为外周栓子的来源可导致严重的发病率和死亡率。有一些针对扩张型心肌病患者的研究表明,尽管患者为窦性心律,但其止血和血小板行为仍发生了改变。左心室收缩功能障碍合并心肌梗死病史的患者,其血栓栓塞的发生率也显著增加。治疗左心室血栓时的临床困境也已得到描述。我们报告一例71岁意大利男性患者,患有扩张型心肌病和心肌梗死病史,其左心室有一个巨大的活动血栓。