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血管移植物研究:合成旁路移植物的内皮细胞种植

Vascular graft research: endothelial cell seeding of synthetic bypass grafts.

作者信息

Fellows E

出版信息

J Vasc Nurs. 1991 Jun;9(2):12-4.

PMID:1859795
Abstract

Over thirty years ago, bypass grafts first became available for human use. This technological development provided patients with improved functioning and quality of life. It is a peculiarity of nature that humans do not heal synthetic bypass grafts with an endothelial lining as other animals will. Researchers have developed the technology to take endothelial cells from a peripheral vein of a person and plant them inside a synthetic bypass graft. Now, science has progress to the point of applied research. In the application of this research to patients, knowledge will be obtained to see if seeding of grafts makes a difference. Hope is on the forefront that peripheral vascular surgery patients may be able to have synthetic grafts that are more like the vessels that they were created with and this will lead to improved functioning and quality living.

摘要

三十多年前,旁路移植物首次可供人类使用。这项技术发展为患者带来了功能改善和生活质量提高。人类无法像其他动物那样用内皮衬里修复合成旁路移植物,这是大自然的一个特性。研究人员已经开发出从人的外周静脉提取内皮细胞并将其植入合成旁路移植物内部的技术。现在,科学已经发展到应用研究阶段。在将这项研究应用于患者的过程中,将会获得相关知识,以了解移植物的内皮化是否会产生影响。人们满怀希望,外周血管手术患者或许能够拥有更类似于自身血管的合成移植物,这将带来功能改善和更高的生活质量。

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Vascular graft research: endothelial cell seeding of synthetic bypass grafts.血管移植物研究:合成旁路移植物的内皮细胞种植
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