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低体重新生儿远端肺动脉导管起源的经皮治疗

Percutaneous treatment of ductal origin of the distal pulmonary artery in low-weight newborns.

作者信息

Butera Gianfranco, Santoro Giuseppe, Calabró Raffaele, Carminati Mario

机构信息

Department of Pediatric Cardiologo, and GUCH Unit, Policlinico San Donato IRCCS, Via Moranti 30, 20097 San Donato Milanese, Italy.

出版信息

J Invasive Cardiol. 2008 Jul;20(7):354, 356.

Abstract

OBJECTIVE

We sought to evaluate the role of percutaneous techniques in the treatment of ductal origin of a distal pulmonary artery (PA) in low-weight infants.

BACKGROUND

Various surgical approaches have been proposed, however, they are highly challenging and risky in neonates.

METHODS

We treated 5 infants weighing < 3 kg with ductal origin of the PA associated with other congenital heart disease. Procedures were performed under general anesthesia and orotracheal intubation.

RESULTS

A total of 7 coronary stents were used. Median procedure and fluoroscopy times were 100 and 8 minutes, respectively. Oxygen saturation increased significantly in all cases (p = 0.026). Both procedural and postprocedural courses were uneventful and the patients were discharged 7-10 days post procedure. During a follow up of 4-12 months, the results remained stable. Two subjects underwent complete corrective surgery 6 months after stent implantation at a weight of 7-9 kg. Ductus arteriosus with the stent inside were completely removed by surgeons who did not report any difficulty. Three subjects await surgery.

CONCLUSION

Percutaneous management of the ductal origin of the pulmonary artery is a safe and efficacious palliative approach.

摘要

目的

我们旨在评估经皮技术在治疗低体重婴儿远端肺动脉(PA)导管起源方面的作用。

背景

已提出多种手术方法,然而,这些方法在新生儿中极具挑战性且风险很高。

方法

我们治疗了5例体重<3 kg且PA导管起源合并其他先天性心脏病的婴儿。手术在全身麻醉和经口气管插管下进行。

结果

共使用了7个冠状动脉支架。手术时间和透视时间中位数分别为100分钟和8分钟。所有病例的血氧饱和度均显著升高(p = 0.026)。手术过程及术后过程均顺利,患者术后7 - 10天出院。在4 - 12个月的随访期间,结果保持稳定。2名受试者在支架植入6个月后,体重达7 - 9 kg时接受了完全矫正手术。外科医生顺利取出了内置支架的心导管,未报告任何困难。3名受试者等待手术。

结论

经皮处理肺动脉导管起源是一种安全有效的姑息治疗方法。

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