de Silva A Prasanna, Vance Thomas P, West Matthew E S, Wright Glenn D
School of Chemistry and Chemical Engineering, Queen's University, Belfast, BT9 5AG, Northern Ireland.
Org Biomol Chem. 2008 Jul 21;6(14):2468-80. doi: 10.1039/b802963f. Epub 2008 May 2.
Using cartoons as an organizational aid, we illustrate how the 'fluorophore-spacer-receptor' format of fluorescent PET (photoinduced electron transfer) sensors and switches can be logically extended in many different directions. These include emissive sensors for various chemical species and properties, and exploit various kinds of emission. Common sensing issues such as dynamic range, internal referencing, selectivity, mapping and space resolution are addressed. The sensory output function is also developed into more complex forms, molecular logic/computation being one such example. Molecular logic leads to molecular arithmetic. Real-life applications to physiological monitoring, medical diagnostics and molecular computational identification of small objects are included.
我们使用卡通作为一种组织辅助手段,来说明荧光正电子发射断层扫描(PET,光致电子转移)传感器和开关的“荧光团-间隔基-受体”形式如何能够在许多不同方向上进行合理扩展。这些扩展包括针对各种化学物质和性质的发光传感器,并利用了各种类型的发射。文中讨论了诸如动态范围、内部参考、选择性、映射和空间分辨率等常见传感问题。传感输出功能也被发展成更复杂的形式,分子逻辑/计算就是这样一个例子。分子逻辑导致了分子算术。文中还包括了在生理监测、医学诊断和小物体的分子计算识别方面的实际应用。