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Strontium ranelate-induced toxic epidermal necrolysis in a patient with post-menopausal osteoporosis.

作者信息

Lee H Y, Lie D, Lim K S, Thirumoorthy T, Pang S M

机构信息

Dermatology Unit, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.

出版信息

Osteoporos Int. 2009 Jan;20(1):161-2. doi: 10.1007/s00198-008-0677-0. Epub 2008 Jul 4.

DOI:10.1007/s00198-008-0677-0
PMID:18600286
Abstract
摘要

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The 10th International Congress on Cutaneous Adverse Drug Reactions, Shimane, Japan, 2018: Focus on New Discoveries.第十届国际皮肤药物不良反应大会，日本岛根，2018年：聚焦新发现
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Increased risk of strontium ranelate-related SJS/TEN is associated with HLA.雷奈酸锶相关的中毒性表皮坏死松解症/重症多形红斑（SJS/TEN）风险增加与人类白细胞抗原（HLA）相关。
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本文引用的文献

1
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures.对全球骨质疏松性骨折的患病率及相关残疾情况的一项评估。
Osteoporos Int. 2006 Dec;17(12):1726-33. doi: 10.1007/s00198-006-0172-4. Epub 2006 Sep 16.
2
Strontium ranelate for preventing and treating postmenopausal osteoporosis.雷奈酸锶用于预防和治疗绝经后骨质疏松症。
Cochrane Database Syst Rev. 2006 Jul 19(3):CD005326. doi: 10.1002/14651858.CD005326.pub2.
3
Strontium ranelate for the treatment of osteoporosis.
骨质疏松症的筛查、诊断与治疗：简要综述
Clin Cases Miner Bone Metab. 2014 Sep;11(3):201-7.
4
Strontium ranelate related Stevens-Johnson syndrome: a case report.雷奈酸锶相关史蒂文斯-约翰逊综合征：一例报告。
Osteoporos Int. 2014 Jun;25(6):1813-6. doi: 10.1007/s00198-014-2688-3. Epub 2014 Apr 1.
5
Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy.发热、皮疹和全身症状：了解病毒和 HLA 在严重皮肤药物过敏中的作用。
J Allergy Clin Immunol Pract. 2014 Jan-Feb;2(1):21-33. doi: 10.1016/j.jaip.2013.11.005.
6
Cutaneous side effects of antiosteoporosis treatments.抗骨质疏松治疗的皮肤副作用。
Ther Adv Musculoskelet Dis. 2011 Feb;3(1):31-41. doi: 10.1177/1759720X10387202.
7
Alopecia associated with strontium ranelate use in a 62-year-old woman.一位 62 岁女性使用雷奈酸锶后出现脱发。
Osteoporos Int. 2013 Mar;24(3):1127-9. doi: 10.1007/s00198-012-1979-9. Epub 2012 Apr 12.
8
Strontium fructose 1,6-diphosphate prevents bone loss in a rat model of postmenopausal osteoporosis via the OPG/RANKL/RANK pathway.果糖 1,6-二磷酸锶通过 OPG/RANKL/RANK 通路预防绝经后骨质疏松症大鼠模型的骨丢失。
Acta Pharmacol Sin. 2012 Apr;33(4):479-89. doi: 10.1038/aps.2011.177. Epub 2012 Mar 19.
9
Extraskeletal benefits and risks of calcium, vitamin D and anti-osteoporosis medications.钙、维生素 D 和抗骨质疏松药物的骨骼外获益与风险。
Osteoporos Int. 2012 Feb;23 Suppl 1(Suppl 1):S1-23. doi: 10.1007/s00198-011-1891-8. Epub 2012 Feb 4.
10
Treatment of osteoporosis: recognizing and managing cutaneous adverse reactions and drug-induced hypersensitivity.骨质疏松症的治疗：识别和管理皮肤不良反应和药物性超敏反应。
Osteoporos Int. 2010 May;21(5):723-32. doi: 10.1007/s00198-009-1097-5. Epub 2009 Nov 17.
BMJ. 2005 Jun 18;330(7505):1400-1. doi: 10.1136/bmj.330.7505.1400.
4
The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis.雷奈酸锶对绝经后骨质疏松症女性椎体骨折风险的影响。
N Engl J Med. 2004 Jan 29;350(5):459-68. doi: 10.1056/NEJMoa022436.