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一位 62 岁女性使用雷奈酸锶后出现脱发。

Alopecia associated with strontium ranelate use in a 62-year-old woman.

机构信息

Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taiwan, Republic of China.

出版信息

Osteoporos Int. 2013 Mar;24(3):1127-9. doi: 10.1007/s00198-012-1979-9. Epub 2012 Apr 12.

DOI:10.1007/s00198-012-1979-9
PMID:22525979
Abstract

Strontium ranelate is an effective drug that was developed for treating osteoporosis. Here, we report the case of a 62-year-old woman who developed headache and diffuse scalp hair loss 1 week after receiving strontium ranelate treatment for osteoporosis. The treatment was subsequently stopped because of the intractable headache. Nevertheless, the patient continued to lose hair for 6 weeks following treatment discontinuation. Histopathological analysis of scalp tissues revealed anagen effluvium. The patient's hair started regrowing slowly 2 months after treatment with strontium ranelate was discontinued.

摘要

雷奈酸锶是一种有效的药物，专门用于治疗骨质疏松症。在此，我们报告了一例 62 岁女性的病例，该患者在接受雷奈酸锶治疗骨质疏松症后 1 周出现头痛和弥漫性头皮脱发。由于顽固的头痛，治疗随后停止。然而，停药后患者仍继续脱发 6 周。头皮组织的组织病理学分析显示生长期脱发。雷奈酸锶治疗停止后 2 个月，患者的头发开始缓慢再生。

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Alopecia associated with strontium ranelate use in a 62-year-old woman.一位 62 岁女性使用雷奈酸锶后出现脱发。
Osteoporos Int. 2013 Mar;24(3):1127-9. doi: 10.1007/s00198-012-1979-9. Epub 2012 Apr 12.
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本文引用的文献

1
Isoniazid-induced alopecia.异烟肼所致脱发。
Lung India. 2011 Jan;28(1):60-1. doi: 10.4103/0970-2113.76304.
2
Strontium ranelate-induced DRESS syndrome with persistent autoimmune hepatitis.
Acta Derm Venereol. 2011 Mar;91(2):205-6. doi: 10.2340/00015555-1014.
3
Strontium ranelate may cause alopecia.雷奈酸锶可能会导致脱发。
BMJ. 2009 Apr 22;338:b1494. doi: 10.1136/bmj.b1494.
4
Strontium ranelate: the first agent of a new therapeutic class in osteoporosis.雷奈酸锶：骨质疏松症治疗新类别中的首个药物。
Adv Ther. 2008 Dec;25(12):1235-56. doi: 10.1007/s12325-008-0125-8.
5
The effects of strontium ranelate in Asian women with postmenopausal osteoporosis.雷奈酸锶对亚洲绝经后骨质疏松症女性的影响。
Calcif Tissue Int. 2008 Nov;83(5):308-14. doi: 10.1007/s00223-008-9180-z. Epub 2008 Oct 9.
6
Strontium ranelate-induced toxic epidermal necrolysis in a patient with post-menopausal osteoporosis.雷奈酸锶致一名绝经后骨质疏松症患者发生中毒性表皮坏死松解症
Osteoporos Int. 2009 Jan;20(1):161-2. doi: 10.1007/s00198-008-0677-0. Epub 2008 Jul 4.
7
Chemotherapy-induced anagen effluvium: diffuse or patterned?化疗引起的生长期脱发：弥漫性还是斑片状？
Dermatology. 2007;215(1):1-2. doi: 10.1159/000102025.
8
Narrative [corrected] review: bisphosphonates and osteonecrosis of the jaws.叙述性（修正后）综述：双膦酸盐与颌骨坏死
Ann Intern Med. 2006 May 16;144(10):753-61. doi: 10.7326/0003-4819-144-10-200605160-00009.
9
Strontium ranelate for the treatment of osteoporosis.
BMJ. 2005 Jun 18;330(7505):1400-1. doi: 10.1136/bmj.330.7505.1400.
10
Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study.雷奈酸锶降低绝经后骨质疏松症女性非椎体骨折风险：外周骨质疏松症治疗（TROPOS）研究。
J Clin Endocrinol Metab. 2005 May;90(5):2816-22. doi: 10.1210/jc.2004-1774. Epub 2005 Feb 22.