Laberge P-Y
Department of Obstetrics and Gynaecology, CHUL, Laval University, S-768 Quebec City, G1V 4G2 Quebec, Canada.
J Gynecol Obstet Biol Reprod (Paris). 2008 Oct;37(6):609-13. doi: 10.1016/j.jgyn.2008.05.006. Epub 2008 Jul 7.
Endometrial ablation (EA) has been performed for the past two decades as an alternative to hysterectomy in women with dysfunctional-uterine bleeding unresponsive to medical treatment. However, unlike hysterectomy, this minimally invasive procedure is not an effective means of contraception. Pregnancy following EA has been reported, but the risks and complications related have not been emphasized. This is a report on two such cases and review of the literature, with a closer look at the frequent negative outcome. A 25-year-old woman underwent EA for dysfunctional-uterine bleeding unresponsive to medical treatment. She had no previous surgery, specifically she had no past myomectomy or caesarean section. She declined concomitant tubal ligation. She became pregnant five years later in early spring 2007 and sustained a large uterine rupture at 24 weeks and died in June 2007 secondary to massive internal bleeding at age 29. A 34-year-old woman with previous hysteroscopic EA became pregnant less than one year after surgery. At that time, she had refused concomitant tubal sterilization since her husband had a vasectomy. Unfortunately, the relationship ended soon after surgery and she had unprotected sexual intercourse with a new partner. Pregnancy termination was complicated by placenta increta, which required immediate abdominal hysterectomy. Pregnancy after EA is not a rare occurrence, regardless of which technique is used. Whether women choose to go on or terminate their pregnancy, this clinical situation can be associated with serious complications and even maternal death. Counselling about contraceptive options at the time of EA is paramount.
在过去二十年中,子宫内膜消融术(EA)一直被用作药物治疗无效的功能失调性子宫出血女性子宫切除术的替代方法。然而,与子宫切除术不同,这种微创手术并非有效的避孕手段。已有EA术后妊娠的报道,但与之相关的风险和并发症尚未得到重视。本文报告两例此类病例并复习文献,深入探讨常见的不良结局。一名25岁女性因药物治疗无效的功能失调性子宫出血接受了EA。她既往无手术史,尤其没有子宫肌瘤切除术或剖宫产史。她拒绝同时进行输卵管结扎。五年后的2007年早春她怀孕了,孕24周时发生子宫大破裂,2007年6月因大量内出血死亡,年仅29岁。一名34岁女性曾接受宫腔镜下EA,术后不到一年怀孕。当时,由于其丈夫已行输精管切除术,她拒绝同时进行输卵管绝育术。不幸的是,术后不久两人关系结束,她与新伴侣发生了无保护性行为。终止妊娠因胎盘植入而复杂化,需要立即行腹式子宫切除术。无论采用何种技术,EA术后妊娠并非罕见。无论女性选择继续妊娠还是终止妊娠,这种临床情况都可能伴有严重并发症甚至孕产妇死亡。EA时提供避孕选择咨询至关重要。