Brunekreef Bert
Institute for Risk Assessment Sciences, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteit Utrecht, PO Box 80178, 3508 TD Utrecht, The Netherlands.
Toxicol Lett. 2008 Aug 15;180(2):118-22. doi: 10.1016/j.toxlet.2008.05.012. Epub 2008 Jul 7.
Epidemiology is the science of public health. Environmental epidemiology specially focuses on human health risks related to exposures in the general (non-occupational) environment. Epidemiology studies may contribute to human risk assessment by identifying hazards, by assessing human exposures to toxicants, and by establishing exposure response functions that can then be used to generate risk assessments. Examples are provided for each of these. The strengths and weaknesses compared to experimental toxicology studies are discussed.
流行病学是公共卫生科学。环境流行病学特别关注与一般(非职业)环境中的暴露相关的人类健康风险。流行病学研究可通过识别危害、评估人类对有毒物质的暴露以及建立随后可用于生成风险评估的暴露反应函数,为人类风险评估做出贡献。文中针对每一项都给出了示例。同时还讨论了与实验毒理学研究相比的优缺点。