Moran J, Addy M, Newcombe R
Dental School, University of Wales College of Medicine, Cardiff.
Clin Prev Dent. 1991 May-Jun;13(3):12-5.
An herbal/bicarbonate toothpaste has received some attention from the public and profession following a number of studies which have reported beneficial effects of the paste on both plaque and gingivitis. The present study, one of several ongoing clinical trials, evaluated the toothpaste in mouthrinse form using a 19-day, no oral hygiene, triple-crossover design in which it was compared with a commercial fluoride toothpaste rinse and the antiplaque mouthrinse chlorhexidine. Over the three periods of the study an increase in plaque and gingivitis was seen for all three products. However, while significant reductions in both parameters were seen with chlorhexidine compared to the toothpastes, there were no significant differences between the herbal and fluoride toothpaste. From these findings it can be concluded that in the long term, the herbal/bicarbonate toothpaste may not exert significant therapeutic effects on plaque and gingivitis beyond that of a conventional commercial paste. Nevertheless, where there is a demand for a natural product, the herbal/bicarbonate paste may be a worthwhile alternative.
在多项研究报告了一种草本/碳酸氢盐牙膏对牙菌斑和牙龈炎均有有益作用之后，该牙膏受到了公众和专业人士的一些关注。本研究是正在进行的多项临床试验之一，采用19天不进行口腔卫生护理的三交叉设计，对漱口水形式的该牙膏进行了评估，将其与一种商用含氟牙膏漱口水以及抗牙菌斑漱口水氯己定进行了比较。在研究的三个阶段中，所有三种产品的牙菌斑和牙龈炎均有所增加。然而，与牙膏相比，氯己定在这两个参数上均有显著降低，而草本牙膏和含氟牙膏之间则没有显著差异。从这些发现可以得出结论，从长期来看，草本/碳酸氢盐牙膏对牙菌斑和牙龈炎可能不会产生超出传统商用牙膏的显著治疗效果。尽管如此，在对天然产品有需求的情况下，草本/碳酸氢盐牙膏可能是一个值得考虑的替代品。
