Shimano Hitoshi, Arai Hidenori, Harada-Shiba Mariko, Ueshima Hirotsugu, Ohta Takao, Yamashita Shizuya, Gotoda Takanari, Kiyohara Yutaka, Hayashi Toshio, Kobayashi Junji, Shimamoto Kazuaki, Bujo Hideaki, Ishibashi Shun, Shirai Koji, Oikawa Shinichi, Saito Yasushi, Yamada Nobuhiro
The Research Committee for Primary Hyperlipidemia, Research on Measures for Intractable Diseases by the Ministry for Health, Labor, and Welfare in Japan.
J Atheroscler Thromb. 2008 Jun;15(3):116-21. doi: 10.5551/jat.e560.
The Japan Atherosclerosis Society (JAS) guidelines for the prevention of atherosclerotic diseases, proposing management for LDL cholesterol as the primary target, have successfully contributed to the prevention of cardiovascular events; however, recently, the impact of hypertriglyceridemia as an additional cardiovascular risk has become understood, especially in light of the rise in obesity, metabolic syndrome, and diabetes in the Japanese population. Rather than waiting to obtain conclusive domestic data confirming that hypertriglyceridemia is a cardiovascular risk factor and that its management is efficacious, we propose guidelines for hypertriglyceridemia using non-HDL cholesterol as a second target.
日本动脉粥样硬化协会（JAS）预防动脉粥样硬化性疾病的指南提出将低密度脂蛋白胆固醇管理作为主要目标，已成功有助于预防心血管事件；然而，最近，高甘油三酯血症作为另一种心血管风险的影响已为人所知，尤其是鉴于日本人群中肥胖、代谢综合征和糖尿病的增加。与其等待获得确凿的国内数据来证实高甘油三酯血症是心血管危险因素且对其管理有效，我们提出以非高密度脂蛋白胆固醇作为第二个目标的高甘油三酯血症指南。
