Joshi S, Bajracharya B L, Baral M R
Department of Paediatrics, KMCTH.
Kathmandu Univ Med J (KUMJ). 2006 Apr-Jun;4(2):232-4.
Kala-azar is a chronic infection of reticuloendothelial system caused by flagellated protozoan, leishmania donovani injected into human host by the bite of the sand fly (phlebotomous) previously infected by biting and sucking the blood of a patient of leishmaniasis. It is characterized by irregular fever of long duration, large spleen and liver, anaemia, leucopenia and progressive emaciation. This article reports a case of a 10 year old girl from Khotang, a nonendemic zone for Kala-azar, who presented with long history of abdominal distension for 11 months, fever for 9 months, cough for a week and weight loss. Clinical examination revealed pallor, enlarged liver and huge splenomegaly. Investigations confirmed the diagnosis of kala-azar by the presence of L.D bodies in bone marrow smear. The patient is being treated with i.v Amphotericin B in Infectious Disease Hospital, Teku.
黑热病是由鞭毛虫原生动物杜氏利什曼原虫引起的网状内皮系统慢性感染,此前感染利什曼病患者血液的白蛉(白蛉属)叮咬人类宿主时将其注入。其特征为长期不规则发热、脾脏和肝脏肿大、贫血、白细胞减少和进行性消瘦。本文报告一例来自黑热病非流行区霍唐的10岁女孩病例,该女孩有11个月的腹胀病史、9个月的发热病史、一周的咳嗽病史和体重减轻。临床检查发现面色苍白、肝脏肿大和巨大脾脏肿大。检查通过骨髓涂片发现利杜体确诊为黑热病。该患者正在特库传染病医院接受静脉注射两性霉素B治疗。