• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[Ofloxacin content in tears following topical use of 0.3% ointment].

作者信息

Zhou J S

机构信息

Shanxi Eye Hospital, Taiyuan.

出版信息

Zhonghua Yan Ke Za Zhi. 1991 Mar;27(2):115-7.

PMID:1860404
Abstract

Tear and aqueous humor levels of ofloxacin following 40mg of topical 0.3% ointment were determined at intervals within 24 hours by high performance liquid chromatography. The highest tear level was detected in half an hour, and effective concentrations existed in 6 hours. The highest aqueous humor level was detected 60 minutes after administration. Ofloxacin ointment produced higher tear concentrations for longer time than did aqueous solution of the drug.

摘要

相似文献

1
[Ofloxacin content in tears following topical use of 0.3% ointment].
Zhonghua Yan Ke Za Zhi. 1991 Mar;27(2):115-7.
2
Amniotic membrane, tear film, corneal, and aqueous levels of ofloxacin in rabbit eyes after amniotic membrane transplantation.羊膜移植后兔眼羊膜、泪膜、角膜及房水中氧氟沙星的含量
Cornea. 2001 Aug;20(6):628-34. doi: 10.1097/00003226-200108000-00014.
3
Penetration of ofloxacin and ciprofloxacin in aqueous humor after topical administration.局部给药后氧氟沙星和环丙沙星在房水中的渗透情况。 （注：原文中“Penetration of ofloxacin and ciprofloxacin in aqueous humor after topical administration.”里多了一个“of”）
Ophthalmic Surg Lasers. 1999 Jun;30(6):465-8.
4
Availability of 0.3% ofloxacin ointment and solution in human conjunctiva and aqueous humor.人结膜和房水中0.3%氧氟沙星眼膏和滴眼液的药物可得性。
J Ocul Pharmacol Ther. 1995 Spring;11(1):57-63. doi: 10.1089/jop.1995.11.57.
5
Tear concentration and safety of levofloxacin ophthalmic solution 1.5% compared with ofloxacin ophthalmic solution 0.3% after topical administration in healthy adult volunteers.左氧氟沙星滴眼液 1.5%与氧氟沙星滴眼液 0.3%在健康成年志愿者局部给药后的泪液浓度和安全性比较。
Cornea. 2010 Mar;29(3):263-8. doi: 10.1097/ICO.0b013e3181b55fce.
6
Comparative tear concentrations of topically applied ciprofloxacin, ofloxacin, and norfloxacin in human eyes.人眼局部应用环丙沙星、氧氟沙星和诺氟沙星后的泪液浓度比较。
Int J Clin Pharmacol Ther. 1997 May;35(5):214-7.
7
Differential aqueous and vitreous concentrations of moxifloxacin and ofloxacin after topical administration one hour before vitrectomy.玻璃体切割术前一小时局部给药后莫西沙星和氧氟沙星在房水和玻璃体中的浓度差异。
Am J Ophthalmol. 2007 Aug;144(2):315-8. doi: 10.1016/j.ajo.2007.03.036.
8
Retinal safety of oral and topical ofloxacin in rabbits.
J Ocul Pharmacol Ther. 1997 Aug;13(4):369-79. doi: 10.1089/jop.1997.13.369.
9
Corneal penetration of fluoroquinolones: aqueous humor concentrations after topical application of levofloxacin 0.5% and ofloxacin 0.3% eyedrops.氟喹诺酮类药物的角膜穿透性：局部应用0.5%左氧氟沙星和0.3%氧氟沙星滴眼液后的房水浓度。
J Cataract Refract Surg. 2005 Jul;31(7):1377-85. doi: 10.1016/j.jcrs.2004.12.063.
10
Flomoxef sodium and levofloxacin concentrations in aqueous humor.眼房水中氟氧头孢钠和左氧氟沙星的浓度。
Ocul Immunol Inflamm. 2005 Apr-Jun;13(2-3):229-34. doi: 10.1080/09273940590928607.