Porto Ana Maria Feitosa, Amorim Melania Maria Ramos de, Coelho Isabela Coutinho Neiva, Santos Luiz Carlos
Instituto Materno Infantil Prof. Fernando Figueira (IMIP), Recife, PE.
Rev Assoc Med Bras (1992). 2008 May-Jun;54(3):242-8. doi: 10.1590/s0104-42302008000300018.
To determine the serologic profile of toxoplasmosis and the main factors associated with susceptibility (patients without IgM and IgG antibodies) in pregnant women attended at a teaching-hospital in Recife, Brasil.
A cross-sectional study was carried out, enrolling 503 pregnant women submitted to serology for toxoplasmosis at IMIP (Recife) from October 2004 to April 2005. Anti-Toxoplasma IgG and IgM antibodies were studied by IFA. A short questionnaire was administered to patients to provide identification, demographic and obstetrical characteristics, past history of morbidity, habits and dwelling conditions. The chi-square and Fisher-exact tests were used at a 5% level of significance.
Immunity for toxoplasmosis was present in 74.7%, susceptibility in 22.5% and "possible" active infection in 2.8% of patients. No significant associations were observed between toxoplasmosis susceptibility and age, location, conditions of morbidity, habits, dwelling conditions and sewage system, living with animals, pregnancy and gestational age. A significant association between toxoplasmosis susceptibility and schooling was found, with a higher frequency of susceptibility among women with eight or more years of schooling.
Susceptibility for toxoplasmosis was relatively low in these prenatal patients and schooling was the only identifiable predictive factor.
确定巴西累西腓一家教学医院就诊的孕妇弓形虫病的血清学特征以及与易感性相关的主要因素（无IgM和IgG抗体的患者）。
开展一项横断面研究，纳入2004年10月至2005年4月在累西腓IMIP接受弓形虫病血清学检测的503名孕妇。通过间接荧光抗体试验研究抗弓形虫IgG和IgM抗体。向患者发放一份简短问卷，以获取其身份信息、人口统计学和产科特征、既往发病史、习惯及居住条件。采用卡方检验和Fisher精确检验，显著性水平为5%。
74.7%的患者对弓形虫病具有免疫力，22.5%的患者易感，2.8%的患者存在“可能的”活动性感染。在弓形虫病易感性与年龄、居住地、发病情况、习惯、居住条件和污水系统、与动物接触、妊娠及孕周之间未观察到显著关联。发现弓形虫病易感性与受教育程度之间存在显著关联，受教育年限为8年及以上的女性中易感性频率更高。
这些产前患者中弓形虫病的易感性相对较低，受教育程度是唯一可识别的预测因素。
Zotero 插件