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发展中国家糖尿病的早期诊断与预防。

Early diagnosis and prevention of diabetes in developing countries.

作者信息

Ambady Ramachandran, Chamukuttan Snehalatha

机构信息

India Diabetes Research Foundation, Dr. A. Ramachandran's Diabetes Hospitals, 28, Marshall's Road, Egmore, Chennai-600 008, India.

出版信息

Rev Endocr Metab Disord. 2008 Sep;9(3):193-201. doi: 10.1007/s11154-008-9079-z. Epub 2008 Jul 7.

Abstract

Type 2 diabetes has an insidious onset with a long latent period of dysglycaemia. By the time the diagnosis of diabetes is made, diabetes-related tissue damage occurs in nearly half of the patients. Even after diagnosis, the glycaemic control is suboptimal in more than 50%, leading to the vascular complications. Evidences suggest that early detection of diabetes by appropriate screening methods, especially in subjects with high risk for diabetes will help to prevent or delay the vascular complications and thus reduce the clinical, social and economic burden of the disease. There are also evidences to show that intervention at the prediabetic stage is superior to diagnosis of diabetes.

摘要

2型糖尿病起病隐匿,血糖异常的潜伏期很长。在确诊糖尿病时,近半数患者已出现糖尿病相关组织损伤。即使在确诊后,超过50%的患者血糖控制仍不理想,进而导致血管并发症。有证据表明,通过适当的筛查方法早期发现糖尿病,尤其是在糖尿病高危人群中,将有助于预防或延缓血管并发症,从而减轻该疾病的临床、社会和经济负担。也有证据表明,在糖尿病前期进行干预优于糖尿病诊断。

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