爱泼斯坦-巴尔病毒的中和作用与该病毒诱导产生的细胞膜抗原抗体之间的关系。
Relation between neutralization of Epstein-Barr virus and antibodies to cell-membrane antigens-induced by the virus.
作者信息
Pearson G, Dewey F, Klein G, Henle G, Henle W
机构信息
Laboratories at The Children's Hospital of Philadelphia, Pennsylvania, USA.
出版信息
J Natl Cancer Inst. 1970 Nov;45(5):989-95.
The neutralization of Epstein-Barr virus (EBV) infectivity by sera with known antibody activities against EBV-associated antigens was investigated in experimentally infected Raji and RPMI 64-10 cells. Antibodies against EBV-induced cell-membrane antigens were apparently responsible for neutralization of viral infectivity. Antibodies against EBV capsid antigens and EBV-induced early antigens were not involved. The implication of these results on the relationship of the membrane antigens to the infectious virus particle is discussed.
在实验感染的拉吉细胞和RPMI 64 - 10细胞中，研究了具有针对EB病毒（EBV）相关抗原的已知抗体活性的血清对EBV传染性的中和作用。针对EBV诱导的细胞膜抗原的抗体显然是病毒传染性中和的原因。针对EBV衣壳抗原和EBV诱导的早期抗原的抗体未参与其中。讨论了这些结果对膜抗原与感染性病毒颗粒关系的影响。
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