针对爱泼斯坦-巴尔病毒决定的膜抗原的抗体依赖性细胞毒性（ADCC）。I. 正常人及急性传染性单核细胞增多症患者血清中的反应性。
Antibody-dependent cellular cytotoxicity (ADCC) against Epstein-Barr virus-determined membrane antigens. I. Reactivity in sera from normal persons and from patients with acute infectious mononucleosis.
作者信息
Jondal M
出版信息
Clin Exp Immunol. 1976 Jul;25(1):1-5.
Abstract
The capacity of antibodies, directed against EBV-determined membrane antigens (MA), to induce antibody-dependent cellular cytotoxicity (ADCC) against EBV superinfected lymphoid cell lines was investigated. Such reactive antibodies were found, at high dilutions, in sera from normal EBV-positive persons but not in sera from EBV-negative persons. Sera from patients with acute infectious mononucleosis (IM), which develop EBV-specific killer T cells, did not induce ADCC. The difference in specificity between ADCC and EBV-specific killer T cells is briefly discussed.
摘要
研究了针对EB病毒（EBV）决定的膜抗原（MA）的抗体诱导针对EBV超感染淋巴母细胞系的抗体依赖性细胞毒性（ADCC）的能力。在高稀释度下，在正常EBV阳性个体的血清中发现了这种反应性抗体，但在EBV阴性个体的血清中未发现。患有急性传染性单核细胞增多症（IM）且产生EBV特异性杀伤性T细胞的患者血清不会诱导ADCC。本文简要讨论了ADCC与EBV特异性杀伤性T细胞之间的特异性差异。
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Antibody-dependent cellular cytotoxicity (ADCC) against Epstein-Barr virus-determined membrane antigens. I. Reactivity in sera from normal persons and from patients with acute infectious mononucleosis.针对爱泼斯坦-巴尔病毒决定的膜抗原的抗体依赖性细胞毒性（ADCC）。I. 正常人及急性传染性单核细胞增多症患者血清中的反应性。
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本文引用的文献
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