Heise Charles P, Kennedy Gregory, Foley Eugene F, Harms Bruce A
Section of Colon and Rectal Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53592, USA.
Dis Colon Rectum. 2008 Dec;51(12):1790-4. doi: 10.1007/s10350-008-9408-z. Epub 2008 Jul 8.
Restorative proctocolectomy has revolutionized the surgical management of ulcerative colitis and familial polyposis syndromes. Though now evolved to include laparoscopy, this approach has not included alternative pouch designs such as ileal S-pouch reconstruction. This comparative analysis evaluated the combination of laparoscopic-assisted total proctocolectomy with an ileal S-pouch design.
One hundred fifty-six (65 laparoscopic-assisted) total proctocolectomy and ileal S-pouch-anal anastomosis procedures performed between 2003 to 2007 were identified from a prospective surgical database. Operative time, length of incision, length of hospital stay, complications, and return of bowel function were examined. A cost analysis including preoperative through postoperative hospital stay and operating room and postanesthesia care unit costs was performed.
The laparoscopic-assisted total proctocolectomy and ileal S-pouch-anal anastomosis procedures were performed for ulcerative colitis in 60 cases and familial adenomatous polyposis in the remaining 5 patients. Four conversions to open technique occurred (6 percent). Comparing laparoscopic and open procedures, the laparoscopic approach took longer to perform than the open technique (mean 451 minutes vs. 347 minutes open; P < 0.001). The mean hospital stay was 6.3 days in the laparoscopic group vs. 8.2 days in the open group (P < 0.001). A detailed cost analysis revealed similar overall costs between the laparoscopic ($18,700) and open approaches ($18,500).
Use of a laparoscopic total proctocolectomy with ileal S-pouch-anal anastomosis reconstruction minimizes incision size and shortens hospital stay. At a teaching academic institution, the laparoscopic approach requires longer operative times yet a negligible cost disadvantage.
保留直肠的结肠切除术彻底改变了溃疡性结肠炎和家族性腺瘤性息肉病综合征的外科治疗方式。尽管现在已发展到包括腹腔镜手术,但这种方法尚未包括替代袋状设计,如回肠S袋重建。本比较分析评估了腹腔镜辅助全直肠结肠切除术与回肠S袋设计的联合应用。
从一个前瞻性手术数据库中识别出2003年至2007年间进行的156例(65例腹腔镜辅助)全直肠结肠切除术和回肠S袋肛管吻合术。检查手术时间、切口长度、住院时间、并发症和肠功能恢复情况。进行了一项成本分析,包括术前至术后住院时间以及手术室和麻醉后护理单元的费用。
60例溃疡性结肠炎患者和其余5例家族性腺瘤性息肉病患者接受了腹腔镜辅助全直肠结肠切除术和回肠S袋肛管吻合术。发生了4例转为开放手术(6%)。比较腹腔镜手术和开放手术,腹腔镜手术的操作时间比开放手术长(平均451分钟对开放手术的347分钟;P<0.001)。腹腔镜组的平均住院时间为6.3天,开放组为8.2天(P<0.001)。详细的成本分析显示,腹腔镜手术(18,700美元)和开放手术(18,500美元)的总体成本相似。
采用腹腔镜全直肠结肠切除术加回肠S袋肛管吻合重建术可使切口尺寸最小化并缩短住院时间。在教学学术机构,腹腔镜手术方法需要更长的手术时间,但成本劣势可忽略不计。