Wade Alexander D, Mathiason Michelle A, Brekke Eric F, Kothari Shanu N
Department of Medical Education, Gundersen Lutheran Medical Foundation, 1900 South Avenue, C03-006B, La Crosse, WI 54601, USA.
J Gastrointest Surg. 2009 Jul;13(7):1260-5. doi: 10.1007/s11605-009-0884-9. Epub 2009 Apr 9.
Standard treatment for ulcerative colitis and prevention of malignancy is total proctocolectomy with a neoileal pouch. The ideal configuration of the pouch has been debated. We hypothesized that there was no difference in quality of life between the J pouch and the W pouch.
We retrospectively reviewed the medical records of all patients undergoing ileoanal anastomosis with pouch construction at a single community-based teaching hospital over an 11+-year period. We collected demographic, operative, and postoperative data and then developed and distributed a survey designed to assess patient quality of life following pouch construction. The data of patients who had J pouches were then compared with those of patients who had W pouches. Forty-nine patients were identified; 30 had J pouches and 19 had W pouches.
The groups did not differ significantly in age, sex, or indication for surgery. Significant differences were detected in readmission rates (J = 63%, W = 21%; p = 0.004) and length of follow-up (J = 61 months, W = 117 months; p = 0.001). Complication rates, length of stay, and conversion to end ileostomy rates were similar between groups. Self-reported health status, activity restrictions, urgency, seepage, protective pad use, and number of bowel movements at night were also similar. A significant difference existed in number of bowel movements per day (J = 6, W = 4.5, p = 0.041). No difference in quality of life was found between groups. Subgroup analysis of ulcerative-colitis-only patients had no effect on results.
Because the J pouch is less technically demanding, it should be the preferred configuration.
溃疡性结肠炎的标准治疗及预防恶变的方法是全直肠结肠切除术并构建回肠储袋。储袋的理想构型一直存在争议。我们假设J型储袋和W型储袋在生活质量方面没有差异。
我们回顾性分析了一家社区教学医院11年多来所有接受回肠肛管吻合术并构建储袋的患者的病历。我们收集了人口统计学、手术及术后数据,然后制定并发放了一项旨在评估储袋构建后患者生活质量的调查问卷。然后将J型储袋患者的数据与W型储袋患者的数据进行比较。共确定了49例患者;30例有J型储袋,19例有W型储袋。
两组在年龄、性别或手术指征方面无显著差异。在再入院率(J型=63%,W型=21%;p = 0.004)和随访时间(J型=61个月,W型=117个月;p = 0.001)方面发现有显著差异。两组之间的并发症发生率、住院时间及转为末端回肠造口术的发生率相似。自我报告的健康状况、活动受限情况、急迫感、渗漏情况、使用护垫情况及夜间排便次数也相似。两组每天的排便次数存在显著差异(J型=6次,W型=4.5次,p = 0.041)。两组在生活质量方面未发现差异。仅对溃疡性结肠炎患者进行亚组分析对结果无影响。
由于J型储袋在技术上要求较低,它应是首选构型。