Fernández-Aceñero M Jesús, Larach Francisca, Ortega-Fernández Consuelo
Department of Surgical Pathology, Hospital General of Móstoles, c/Río Júcar s/n, Móstoles, Madrid, Spain.
Acta Otolaryngol. 2009 Jan;129(1):108-12. doi: 10.1080/00016480802008207.
In this report we review the diagnosis, therapy, and outcome of laryngeal non-epithelial tumors and comment on the literature on these rare lesions.
Non-epithelial tumors of the larynx are rather rare and most cases have been reported as isolated or short series of cases from different centers all over the world. The aim of the present study was to review the 10-year experience with non-epithelial lesions in a 400-bed tertiary hospital covering a population of almost 250 000 people in Madrid, Spain.
We reviewed 2631 laryngeal samples corresponding to this time period.
In all, 737 corresponded to carcinomas (726 squamous cell carcinomas). We had two cases of chondrosarcoma, one case of liposarcoma, one case of synovial sarcoma, and one neural benign tumor, suggestive of neurinoma. In this period we also had an inflammatory pseudotumor affecting the vocal cord, a case of primary laryngeal extramedullary plasmocytoma, and one case of high grade diffuse malignant lymphoma with exclusive involvement of the larynx. In our series most patients were women (five vs three patients) and ages ranged between 12 and 92 years.
在本报告中，我们回顾了喉非上皮性肿瘤的诊断、治疗及预后情况，并对有关这些罕见病变的文献进行了评述。
喉非上皮性肿瘤相当罕见，大多数病例都是世界各地不同中心报告的孤立病例或少数病例系列。本研究的目的是回顾一家拥有400张床位的三级医院10年来处理非上皮性病变的经验，该医院覆盖西班牙马德里近25万人。
我们回顾了这一时期的2631份喉部样本。
总共737份样本为癌（726份为鳞状细胞癌）。我们有2例软骨肉瘤、1例脂肪肉瘤、1例滑膜肉瘤和1例神经良性肿瘤，提示为神经鞘瘤。在此期间，我们还有1例影响声带的炎性假瘤、1例原发性喉髓外浆细胞瘤以及1例仅累及喉部的高级别弥漫性恶性淋巴瘤。在我们的系列病例中，大多数患者为女性（5例对3例），年龄在12岁至92岁之间。
