Walker L, DeMeulemeester C
Neuropsychology Service, The Ottawa Hospital - General Campus, Canada.
Clin Neuropsychol. 2008 Dec;22(6):1035-53. doi: 10.1080/13854040701874386. Epub 2008 Apr 8.
F.D. exhibited the cognitive and behavioral profile of frontotemporal dementia in the context of spontaneous intracranial hypotension (SIH). Symptoms included orthostatic headache, as well as cognitive and personality changes. He underwent CT, EEG, and MRI as well as neuropsychological evaluations before and after corticosteroid treatment. The initial evaluation documented significant cognitive impairment with a predominance of executive dysfunction. Following treatment, a second evaluation revealed marked improvement in cognition and behavior. Rapid diagnosis and treatment can yield a favorable outcome. Both quantitative and qualitative information from measures of executive functioning were discussed, as well as their anatomical substrates.
F.D.在自发性颅内低压（SIH）的背景下表现出额颞叶痴呆的认知和行为特征。症状包括体位性头痛以及认知和人格改变。他在皮质类固醇治疗前后接受了CT、脑电图和MRI以及神经心理学评估。初始评估记录了以执行功能障碍为主的显著认知障碍。治疗后，第二次评估显示认知和行为有明显改善。快速诊断和治疗可产生良好结果。讨论了来自执行功能测量的定量和定性信息及其解剖学基础。
