McNally M E, Atkinson S A, Cole D E
Department of Pediatrics, Dalhousie University, Halifax, NS, Canada.
J Nutr. 1991 Aug;121(8):1250-4. doi: 10.1093/jn/121.8.1250.
Colostrum (d 2-4) and mature human milk samples (d 23-30) collected from eight mothers giving birth at 31 +/- 7 wk of gestation were analyzed for total sulfur, free inorganic sulfate and acid labile sulfoesters. The data presented are representative of complete 24-h expressions. Total sulfur was measured using a wet digestion procedure in which all forms of sulfur were converted to inorganic sulfate. The sulfate was quantified by a radiometric barium precipitation assay. Total sulfur showed no marked diurnal variation, but the mean concentration in 19 colostrum samples (10.2 +/- 4.2 mmol/L) was significantly higher than in 14 mature milk samples (4.3 +/- 0.8 mmol/L) (P less than 0.001). The range of predicted 24-h intakes of sulfur by infants fed colostrum (0.78-3.22 mmol/kg body weight) was slightly higher than those fed mature milk (0.54-1.06 mmol/kg), but it was not significantly different. The combined fractions of free inorganic sulfate and acid-labile sulfoester fractions contribute less than 5% to the total sulfur content of either colostrum or mature milk. However, the physiological significance of these milk components remains to be determined.
对从8名妊娠31±7周分娩的母亲收集的初乳（第2 - 4天）和成熟人乳样本（第23 - 30天）进行了总硫、游离无机硫酸盐和酸不稳定硫酯的分析。呈现的数据代表了24小时的完整泌乳量。总硫采用湿消化法测定，其中所有形式的硫都转化为无机硫酸盐。通过放射性钡沉淀法对硫酸盐进行定量。总硫没有明显的昼夜变化，但19份初乳样本中的平均浓度（10.2±4.2 mmol/L）显著高于14份成熟乳样本中的平均浓度（4.3±0.8 mmol/L）（P＜0.001）。食用初乳的婴儿预测24小时硫摄入量范围（0.78 - 3.22 mmol/kg体重）略高于食用成熟乳的婴儿（0.54 - 1.06 mmol/kg），但差异不显著。游离无机硫酸盐和酸不稳定硫酯部分的总和在初乳或成熟乳的总硫含量中所占比例不到5%。然而，这些乳汁成分的生理意义仍有待确定。
