Werner Clément M L, Pierpont Yvonne, Pollak Andrew N
Department of Orthopaedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
J Am Acad Orthop Surg. 2008 Jul;16(7):369-75. doi: 10.5435/00124635-200807000-00002.
Emergent débridement of open fractures within 6 hours of injury has long been considered to be critical to prevention of infection. The basis for this mandate is unclear, however. In clinical practice, physiologic and logistical challenges frequently limit the degree to which such emergent surgical care can effectively be rendered. Furthermore, concerns exist that quality of care might be improved when services are performed during normal working hours. The current literature suggests no obvious advantage to performing surgical débridement within 6 hours after injury versus doing so between 6 and 24 hours after injury. The effect of delays >24 hours is unclear. Further research in this area would be helpful, but development of definitive level I evidence seems unlikely. Surgical débridement of open fractures should be accomplished urgently, as soon as the patient's physiologic condition permits and as soon as appropriate resources are available to safely perform the procedure.
长期以来,人们一直认为在受伤后6小时内对开放性骨折进行急诊清创对于预防感染至关重要。然而,这一要求的依据尚不清楚。在临床实践中,生理和后勤方面的挑战常常限制了这种急诊手术治疗能够有效实施的程度。此外,有人担心在正常工作时间进行手术可能会提高护理质量。目前的文献表明,在受伤后6小时内进行手术清创与在受伤后6至24小时内进行手术清创相比,没有明显优势。超过24小时延迟的影响尚不清楚。该领域的进一步研究将有所帮助,但似乎不太可能获得确凿的一级证据。一旦患者的生理状况允许且有适当资源可安全进行手术,应尽快对开放性骨折进行手术清创。