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下肢开放性骨折:当前的治疗方法及临床结果

Open fractures of the lower extremity: Current management and clinical outcomes.

作者信息

Elniel Abdel Rahim, Giannoudis Peter V

机构信息

Leeds Teaching Hospitals Trust, UK.

Academic Department of Trauma and Orthopaedics, Leeds Teaching Hospitals, University of Leeds, UK; NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, UK.

出版信息

EFORT Open Rev. 2018 May 21;3(5):316-325. doi: 10.1302/2058-5241.3.170072. eCollection 2018 May.

Abstract

Open fractures of the lower extremity are the most common open long bone injuries, yet their management remains a topic of debate.This article discusses the basic tenets of management and the subsequent impact on clinical outcome. These include the rationale for initial debridement, antimicrobial cover, addressing the soft-tissue injury and definitive skeletal management.The classification of injury severity continues to be a useful tool in guiding treatment and predicting outcome and prognosis. The Gustilo-Anderson classification continues to be the mainstay, but the adoption of severity scores such as the Ganga Hospital score may provide additional predictive utility.Recent literature has challenged the perceived need for rapid debridement within 6 hours and the rationale for prolonged antibiotic therapy in the open fracture. The choice of definitive treatment must be decided against known efficacy and injury severity/type.Recent data demonstrate better outcomes with internal fixation methods in most open tibial fractures, but external fixation continues to be an appropriate choice in more severe injuries. The incidence of infection and non-union has decreased with new treatment approaches but continues to be a source of significant morbidity and mortality.Assessment of functional outcome using various measures has been prevalent in the literature, but there is limited consensus regarding the best measures to be used. Cite this article: 2018;3 DOI: 10.1302/2058-5241.3.170072.

摘要

下肢开放性骨折是最常见的开放性长骨损伤,但其治疗方法仍存在争议。本文讨论了治疗的基本原则及其对临床结果的后续影响。这些原则包括初期清创、抗菌覆盖、处理软组织损伤以及确定性骨骼治疗的基本原理。损伤严重程度分类仍然是指导治疗以及预测结果和预后的有用工具。 Gustilo-Anderson分类法仍然是主要方法,但采用如Ganga医院评分等严重程度评分可能会提供额外的预测价值。最近的文献对6小时内快速清创的必要性以及开放性骨折中延长抗生素治疗的基本原理提出了质疑。必须根据已知的疗效以及损伤严重程度/类型来决定确定性治疗的选择。最近的数据表明,在大多数开放性胫骨骨折中,内固定方法能取得更好的结果,但在更严重的损伤中,外固定仍然是一种合适的选择。随着新治疗方法的出现,感染和骨不连的发生率有所下降,但仍然是导致严重发病和死亡的原因。文献中普遍使用各种方法评估功能结果,但对于最佳评估方法的共识有限。引用本文:2018;3 DOI: 10.1302/2058-5241.3.170072 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4252/5994617/2024f6b2a874/eor-3-316-g001.jpg

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