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左冠状动脉口异位起源于左心室并伴有闭塞膜:一种先前未报道的异常情况及胚胎学解释。

Ectopic origin of left coronary ostium from left ventricle, with occlusive membrane: a previously unreported anomaly, with an embryologic interpretation.

作者信息

Pirelli Luigi, Yu Pey-Jen, Srichai Monvadi B, Khvilivitzky Katherine, Angelini Paolo, Grau Juan B

机构信息

Department of Cardiothoracic Surgery, Division of Cardiology, New York University Medical Center, New York, New York 10016, USA.

出版信息

Tex Heart Inst J. 2008;35(2):162-5.

PMID:18612445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2435451/
Abstract

Congenital atresia of the left main coronary artery, a condition in which the left main trunk is developed but has been occluded since birth, is a rare coronary anomaly. Herein, we describe this anomaly's association with a subannular location of an obliterated left main ostium in a patient with a bicuspid aortic valve and severe aortic stenosis. The patient underwent successful surgery. We discuss the embryologic implications of congenital atresia of the left main coronary artery, in view of the exceptional anatomic features of this condition. To our knowledge, this is the 1st report of a left coronary artery that was found to arise from the left ventricle.

摘要

左冠状动脉先天性闭锁是一种罕见的冠状动脉异常,其左主干已发育,但自出生以来就已闭塞。在此,我们描述了一名患有二叶式主动脉瓣和严重主动脉狭窄的患者中,这种异常与闭锁的左主开口瓣下位置的关联。该患者手术成功。鉴于这种情况特殊的解剖特征,我们讨论了左冠状动脉先天性闭锁的胚胎学意义。据我们所知,这是首次报告左冠状动脉起源于左心室。

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Tex Heart Inst J. 2008;35(2):162-5.
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本文引用的文献

1
Surgical management of congenital obstruction of the left main coronary artery with supravalvular aortic stenosis.先天性左主冠状动脉梗阻合并瓣上主动脉狭窄的外科治疗
J Thorac Cardiovasc Surg. 2000 Dec;120(6):1040-6. doi: 10.1067/mtc.2000.110493.
2
Left main coronary artery atresia: literature review and therapeutical considerations.左冠状动脉主干闭锁:文献综述与治疗考量
Eur J Cardiothorac Surg. 1997 Mar;11(3):505-14. doi: 10.1016/s1010-7940(96)01121-9.
3
Coronary artery anomalies and bicuspid aortic valves in the Syrian hamster.叙利亚仓鼠的冠状动脉异常和二叶式主动脉瓣
Basic Res Cardiol. 1991 Mar-Apr;86(2):148-53. doi: 10.1007/BF02190547.