Sans-Coma V, Arqué J M, Durán A C, Cardo M, Fernández B
Departamento de Biología Animal (Zoología), Universidad de Málaga, Spain.
Basic Res Cardiol. 1991 Mar-Apr;86(2):148-53. doi: 10.1007/BF02190547.
The condition of coronary arteries and aortic valves was studied in 552 Syrian hamsters belonging to a single family subjected to high endogamous pressure. The study was carried out using a corrosion-cast technique. In 178 hamsters the aortic valve was bicuspid. In 138 specimens, 54 of them with normal aortic valves and 84 with bicuspid aortic valves, anomalies in the origin of the coronary arteries could be classified in three morphologic types: left coronary artery from the pulmonary trunk (36 cases); single right coronary artery (84 cases); left coronary artery from the dorsal aortic sinus (18 cases). Results of a chi 2 contingency test show that the frequency of left coronary artery from the pulmonary trunk and single right coronary artery significantly increases when the aortic valve is bicuspid. The present findings suggest that there is a developmental complex consisting of biscuspid aortic valve and anomalous origin of the coronary arteries.
对552只来自单一家庭且承受高度近亲繁殖压力的叙利亚仓鼠的冠状动脉和主动脉瓣状况进行了研究。该研究采用了腐蚀铸型技术。在178只仓鼠中，主动脉瓣为二叶式。在138个标本中，其中54个主动脉瓣正常，84个主动脉瓣为二叶式，冠状动脉起源异常可分为三种形态类型：发自肺动脉干的左冠状动脉（36例）；单一右冠状动脉（84例）；发自背主动脉窦的左冠状动脉（18例）。卡方列联检验结果表明，当主动脉瓣为二叶式时，发自肺动脉干的左冠状动脉和单一右冠状动脉的频率显著增加。目前的研究结果表明，存在一种由二叶式主动脉瓣和冠状动脉起源异常组成的发育复合体。
