Stanzani Lorenzo, Fusi Laura, Gomitoni Antonella, Roncoroni Mauro, Villa Paolo, Grampa Giampiero
Unità Operativa di Neurologia, Presidio Ospedaliero di Saronno Azienda Ospedaliera Ospedale di Circolo di Busto Arsizio, Piazzale Borella 1, Saronno, Italy.
Neurol Sci. 2008 Jun;29(3):163-7. doi: 10.1007/s10072-008-0929-y. Epub 2008 Jul 9.
Posterior reversible encephalopathy is a distinctive syndrome associated with different diseases and drugs. Disease evolution is frequently favorable with an adequate treatment. Damage typically involves parietal-occipital lobes even if a more anterior diffusion has been described. Here, we report the case of a woman affected by Polyarteritis Nodosa, who suddenly complicated with decreased consciousness and seizures, during an acute hypertensive state. MRI imaging showed increased T2 and FLAIR signal in posterior regions. Her neurological evolution was positive, according to arterial pressure correction, although the systemic vasculitis was still ongoing, hence affecting final prognosis.
后部可逆性脑病是一种与不同疾病和药物相关的独特综合征。通过适当治疗,疾病进展通常良好。即使曾有更靠前部位扩散的描述,但损伤通常累及顶枕叶。在此,我们报告一例结节性多动脉炎女性患者,在急性高血压状态下突然出现意识减退和癫痫发作。MRI成像显示后部区域T2和液体衰减反转恢复序列(FLAIR)信号增强。尽管系统性血管炎仍在进展,从而影响最终预后,但根据动脉压校正情况,她的神经功能进展呈阳性。