Hodgson David M, Hughes Steven P, Thompson Amber L, Heightman Tom D
Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
Org Lett. 2008 Aug 21;10(16):3453-6. doi: 10.1021/ol801224g. Epub 2008 Jul 10.
N-tert-Butylsulfonyl and N-tert-butylsulfinyl aziridine undergo alpha-lithiation/electrophile trapping providing a new entry to terminal aziridines. With N-tert-butylsulfinyl aziridine complete asymmetric induction is observed alpha to nitrogen.
N-叔丁基磺酰基氮丙啶和N-叔丁基亚磺酰基氮丙啶发生α-锂化/亲电试剂捕获反应，为合成末端氮丙啶提供了一条新途径。对于N-叔丁基亚磺酰基氮丙啶，在氮的α位观察到了完全的不对称诱导。
