Atlantis Evan, Martin Sean A, Haren Matthew T, Taylor Anne W, Wittert Gary A
Exercise, Health and Performance Faculty Research Group, Faculty of Health Sciences, University of Sydney, Sydney, Australia.
Am J Clin Nutr. 2008 Jul;88(1):95-104. doi: 10.1093/ajcn/88.1.95.
Age-related change in body composition is associated with adverse health outcomes, including functional decline, disability, morbidity, and early mortality. Prevention of age-related changes requires a greater understanding of the associations among age, lifestyle factors, and body composition.
We aimed to comprehensively determine lifestyle factors associated with age-related differences in body composition assessed by using dual-energy X-ray absorptiometry.
We analyzed baseline (cross-sectional) data collected from 2002 to 2005 for approximately 1200 men in the Florey Adelaide Male Aging Study, a regionally representative cohort of Australian men aged 35-81 y.
Mean values for whole-body lean mass (LM) and areal bone mineral density (aBMD) decreased, whereas mean values for abdominal fat mass (FM) and whole-body and abdominal percentage FM (%FM) increased with age. No significant age-related differences were found for whole-body FM. Multiple adjusted odds of being in the highest tertiles for whole-body and abdominal %FM decreased for smokers (63-71%) but increased with age group and for lowest energy (43-50%), carbohydrate (92-107%), and fiber (107%) intake tertiles. Multiple adjusted odds of being in the highest aBMD tertile decreased for lowest body mass (92%) and carbohydrate intake (63%) tertiles and for men aged > or = 75 y (78%) but increased for Australian birth (58%) and for participation in vigorous physical activities (82%).
Age-related differences in body composition indicate that whole-body FM remains stable but increases viscerally and that whole-body %FM is confounded by LM, whereas aBMD decreases with age. Age-related differences in %FM and aBMD are associated with demographic and lifestyle factors.
身体成分的年龄相关变化与不良健康结局相关，包括功能衰退、残疾、发病率和过早死亡。预防年龄相关变化需要更深入了解年龄、生活方式因素和身体成分之间的关联。
我们旨在全面确定与使用双能X线吸收法评估的身体成分年龄相关差异相关的生活方式因素。
我们分析了2002年至2005年从弗洛里阿德莱德男性衰老研究中收集的约1200名男性的基线（横断面）数据，该研究是澳大利亚35 - 81岁男性的具有区域代表性的队列研究。
随着年龄增长，全身瘦体重（LM）和面积骨密度（aBMD）的平均值下降，而腹部脂肪量（FM）以及全身和腹部脂肪百分比（%FM）的平均值增加。全身FM未发现明显的年龄相关差异。吸烟者全身和腹部%FM处于最高三分位数的多重调整比值降低（63 - 71%），但随年龄组增加，且在能量摄入最低（43 - 50%）、碳水化合物摄入最低（92 - 107%）和纤维摄入最低（107%）三分位数时增加。aBMD处于最高三分位数的多重调整比值在体重最低（92%）和碳水化合物摄入最低（63%）三分位数以及年龄≥75岁的男性中降低（78%），但在澳大利亚出生的男性中升高（58%）以及在参与剧烈体育活动的男性中升高（82%）。
身体成分的年龄相关差异表明全身FM保持稳定但内脏脂肪增加，全身%FM受LM影响，而aBMD随年龄下降。%FM和aBMD的年龄相关差异与人口统计学和生活方式因素有关。
