Tan Teng-Yeow, Chen Ting-Yao
Department of Neurology, Cerebrovascular Disease Section, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung 833, Taiwan.
J Clin Ultrasound. 2008 Sep;36(7):422-6. doi: 10.1002/jcu.20515.
Microembolic signals (MES) can be detected in a variety of clinical situations using conventional transcranial Doppler (TCD) sonography. We studied the prevalence of positive MESs in acute stroke patients with intracranial artery stenosis using power M-mode Doppler (PMD) sonography and also tested the feasibility of this new technique.
Thirty-three consecutive acute ischemic stroke or transient ischemic attack patients with intracranial large artery occlusive disease were enrolled. PMD/TCD monitoring for 30 minutes was used for MES detection downstream of the stenotic artery within 1 week after stroke onset. Clinical risk factors in emboli-positive and emboli-negative patients were assessed.
MESs were detected in 21% (7/33) of patients. No significant differences were found in clinical risk factors between emboli-positive and emboli-negative patients.
PMD sonography to detect MESs in acute stroke patients is feasible and may be used in future clinical trials regarding MES detection.
使用传统经颅多普勒（TCD）超声检查可在多种临床情况下检测到微栓子信号（MES）。我们使用功率M型多普勒（PMD）超声检查研究了颅内动脉狭窄的急性卒中患者中阳性MES的发生率，并测试了这项新技术的可行性。
连续纳入33例患有颅内大动脉闭塞性疾病的急性缺血性卒中或短暂性脑缺血发作患者。在卒中发作后1周内，使用PMD/TCD监测30分钟，以检测狭窄动脉下游的MES。评估栓子阳性和栓子阴性患者的临床危险因素。
21%（7/33）的患者检测到MES。栓子阳性和栓子阴性患者的临床危险因素无显著差异。
PMD超声检查在急性卒中患者中检测MES是可行的，可用于未来关于MES检测的临床试验。
