经颅多普勒超声微栓子检测在颅内狭窄-闭塞性疾病中的临床应用。
Clinical utilization of microembolus detection by transcranial Doppler sonography in intracranial stenosis-occlusive disease.
机构信息
Department of Neurology, First Bethune Hospital of Jilin University, Changchun, Jilin 130021, China.
出版信息
Chin Med J (Engl). 2013 Apr;126(7):1355-9.
OBJECTIVE
To discuss the clinical ultiliazation and significance of microembolus detection by transcranial Doppler (TCD) sonography in intracranial stenosis-occlusive disease.
DATA SOURCES
All related articles in this review were mainly searched from PubMed published in English from 1996 to 2012 using the terms of microembolic signal, transcranial Doppler, intracranial stenosis, stroke.
STUDY SELECTION
Original articles and reviews were selected if they were related to the clinical utilization of microembolus detection in intracranial stenosis-occlusive disease.
RESULTS
Intracranial stenosis is a significant cause of cerebral emboli, and microembolus detection by TCD sonography were widely used in exploring the mechanisms of ischemic stroke with intracranial stenosis (including the middle cerebral artery stenosis and the vertebral-basilar stenosis), evaluating the prognosis of acute stroke, evaluating the therapeutic effects, and predicting the recurrent events of stroke.
CONCLUSION
Microembolus detection by TCD sonography plays an important role in the cerebral ischemic stroke patients with intracranial stenosis.
目的
探讨经颅多普勒超声（TCD）微栓子检测在颅内狭窄-闭塞性疾病中的临床应用及意义。
资料来源
检索 1996 年至 2012 年发表在 PubMed 上的英文文献，检索词为 microembolic signal、transcranial Doppler、intracranial stenosis、stroke，主要纳入与颅内狭窄性疾病中微栓子检测的临床应用相关的文章。
研究选择
纳入标准为与颅内狭窄性疾病中微栓子检测的临床应用相关的原始研究和综述。
结果
颅内狭窄是引起脑栓塞的重要原因，TCD 微栓子检测广泛应用于探讨伴有颅内狭窄（包括大脑中动脉狭窄和椎基底动脉狭窄）的缺血性脑卒中的发病机制、评估急性脑卒中的预后、评价治疗效果和预测脑卒中的复发事件。
结论
TCD 微栓子检测在颅内狭窄性脑缺血性脑卒中患者中具有重要作用。
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