Yu Shichao, Chie Yu-Ming, Guan Zheng-Hui, Zhang Xumu
Department of Chemistry and Chemical Biology and Department of Pharmaceutical Chemistry, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854-8020, USA.
Org Lett. 2008 Aug 21;10(16):3469-72. doi: 10.1021/ol801247v. Epub 2008 Jul 11.
A series of new pyrrole-based tetraphosphorus ligands were synthesized and used for Rh-catalyzed isomerization-hydroformylation of internal olefins. It was found that the substituents at the 3,3',5,5'-positions of the biphenyl greatly effected the linear selectivity, and the alkyl-substituted tetraphosphorus ligands gave the best results (for 2-octene, n: i up to 207, for 2-hexene, n: i up to 362).
合成了一系列基于吡咯的新型四磷配体，并将其用于铑催化的内烯烃异构化氢甲酰化反应。发现联苯3,3',5,5'-位的取代基对线性选择性有很大影响，烷基取代的四磷配体效果最佳（对于2-辛烯，正异比高达207；对于2-己烯，正异比高达362）。
