Zhang Hong-Jun, Tang Xiao-Yun, Ju Bao-Ling, Song Bao-Hui
Department of Pathogenic Biology, Mudanjiang Medical College, Mudanjiang 157011, China.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008 Jul;24(7):683-5.
To explore the effect of yupingfengsan on the growth of tumor and immunological function in tumor-bearing mice.
The models of tumor-bearing mice were established by inoculating the healthy mice with S180 tumor carneus cells cultured in vitro. Then the ratio of tumor restriction was calculated. The phagocytosis activity of phagocytes, the level of NO secreted by phagocytes, the proliferating activity of T lymphocytes and the level of IL-2 were detected in the mice after being treated with yupingfengsan 12 days.
yupingfengsan elevated the phagocytosis of phagocytes and the level of NO secreted by phagocytes. It promoted T lymphocytes to transform, and increased the level of IL-2 and the activity of NK cells.
yupingfengsan can increase the immunological function of tumor-bearing mice and suppress the development of tumor in mice.
探讨玉屏风散对荷瘤小鼠肿瘤生长及免疫功能的影响。
通过给健康小鼠接种体外培养的S180肉瘤细胞建立荷瘤小鼠模型。然后计算肿瘤抑制率。在给予玉屏风散12天后，检测小鼠吞噬细胞的吞噬活性、吞噬细胞分泌的NO水平、T淋巴细胞的增殖活性及IL-2水平。
玉屏风散提高了吞噬细胞的吞噬作用及吞噬细胞分泌的NO水平。它促进T淋巴细胞转化，增加IL-2水平及NK细胞活性。
玉屏风散可增强荷瘤小鼠的免疫功能并抑制小鼠肿瘤的发展。
